2-(5-Methyl-pyrazol-1-yl)-ethylamine

Base Information

• Chemical Name: 2-(5-Methyl-pyrazol-1-yl)-ethylamine
• CAS No.: 101395-72-6
• Molecular Formula: C6H11N3
• Molecular Weight: 125.173
• Hs Code.: 2933199090
• DSSTox Substance ID: DTXSID30390108
• Wikidata: Q82186534
• Mol file: 101395-72-6.mol

Synonyms:101395-72-6;2-(5-Methyl-pyrazol-1-yl)-ethylamine;2-(5-methyl-1H-pyrazol-1-yl)ethanamine;2-(5-methylpyrazol-1-yl)ethanamine;1H-Pyrazole-1-ethanamine, 5-methyl-;2-(5-methyl-1H-pyrazol-1-yl)ethan-1-amine;SCHEMBL1822155;DTXSID30390108;HMS1704F11;BEA39572;BBL030322;MFCD05053631;STK346873;2-(5-methylpyrazol-1-yl)ethyl amine;AKOS000312126;VS-09741;BB 0260930;CS-0282024;FT-0677681;EN300-230171;2-(5-methyl-pyrazol-1-yl)-ethylamine, AldrichCPR

Chemical Property of 2-(5-Methyl-pyrazol-1-yl)-ethylamine

Chemical Property:

• Boiling Point: 68 °C(Press: 1 Torr)
• PKA: 8.97±0.10(Predicted)
• PSA: 43.84000
• Density: 1.047 g/cm3
• LogP: 0.85050
• Storage Temp.: 2-8°C
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 125.095297364
• Heavy Atom Count: 9
• Complexity: 84.4

Purity/Quality:

98%min ^*data from raw suppliers

2-(5-Methyl-pyrazol-1-yl)-ethylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=NN1CCN

Technology Process of 2-(5-Methyl-pyrazol-1-yl)-ethylamine

There total 1 articles about 2-(5-Methyl-pyrazol-1-yl)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-(β-aminoethyl)-5-methyl-1H-pyrazole (101395-72-6)

Guidance literature:

3(5)-Methyl-pyrazol, 1-Amino-2-chlor-athan-hydrochlorid in Toluol: 20 stundigen Erwarmen;

Reference yield: 70.0%

(R,S)-2-[4-(trifluoromethanesulfonyloxy)phenyl]-2-fluoro-propanoic acid (1034809-02-3) + 1-(β-aminoethyl)-5-methyl-1H-pyrazole (101395-72-6) → 4-(2-fluoro-1-{[2-(5-methyl-1H-pyrazol-1-yl)ethyl]amino}-1-oxopropan-2-yl)phenyl trifluoromethanesulfonate (1299294-27-1)

Guidance literature:

(R,S)-2-[4-(trifluoromethanesulfonyloxy)phenyl]-2-fluoro-propanoic acid; With thionyl chloride; for 3h; Reflux;

1-(β-aminoethyl)-5-methyl-1H-pyrazole; In tetrahydrofuran; at 0 - 20 ℃;

Downstream raw materials:

4-(2-fluoro-1-{[2-(5-methyl-1H-pyrazol-1-yl)ethyl]amino}-1-oxopropan-2-yl)phenyl trifluoromethanesulfonate