4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol

Base Information

Chemical Name:4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol
CAS No.:101432-05-7
Molecular Formula:C16H18O4
Molecular Weight:274.317
Hs Code.:
ChEMBL ID:CHEMBL245952
DSSTox Substance ID:DTXSID50564723
Nikkaji Number:J2.948.449J
Wikidata:Q82449531
Mol file:101432-05-7.mol

Synonyms:101432-05-7;CHEMBL245952;4-[4-(3,4-DIHYDROXYPHENYL)BUTYL]BENZENE-1,2-DIOL;4-(4-(3,4-dihydroxyphenyl)butyl)benzene-1,2-diol;1,4-BIS(3,4-DIHYDROXYPHENYL)BUTANE;SCHEMBL2307446;DTXSID50564723;BDBM50212958;4,4'-(Butane-1,4-diyl)di(benzene-1,2-diol)

Suppliers and Price of 4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol

Chemical Property:

PSA：80.92000
LogP:3.07440
XLogP3:3.7
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:274.12050905
Heavy Atom Count:20
Complexity:256

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CCCCC2=CC(=C(C=C2)O)O)O)O

Technology Process of 4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol

There total 23 articles about 4-[4-(3,4-Dihydroxyphenyl)butyl]benzene-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 51487-58-2
1,4-bis(3,4-dimethoxyphenyl)butane

: 101432-05-7
4,4’-(butane-1,4-diyl)bis(benzene-1,2-diol)

Guidance literature:: With boron tribromide;

Reference yield: 56.0%

: 4-[4-(3,4-dimethoxyphenyl)butyl]benzene-1,2-diol

: 101432-05-7
4,4’-(butane-1,4-diyl)bis(benzene-1,2-diol)

Guidance literature:: With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2019.111910

Reference yield:

: 13575-74-1
4-(3,4-dimethoxyphenyl)butanoic acid

: 101432-05-7
4,4’-(butane-1,4-diyl)bis(benzene-1,2-diol)

Guidance literature:: Multi-step reaction with 8 steps

1: 89 percent / lithium aluminum hydride / tetrahydrofuran / 3.5 h / 20 °C

2: 77 percent / pyridinium chlorochromate / CH₂Cl₂ / 1 h / 20 °C

3: 76 percent / tetrahydrofuran / -78 - 20 °C

4: 62 percent / pyridinium chlorochromate / CH₂Cl₂ / 1 h / 20 °C

5: hydrazine hydrate / ethanol / 4 h / Heating

6: 0.0154 g / potassium t-butoxide / dimethylsulfoxide / 20 h / 20 °C

7: 0.072 g / aq. NaOH / methanol / 1 h / 100 °C

8: 47 percent / BBr₃ / CH₂Cl₂ / 0.5 h / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; potassium tert-butylate; boron tribromide; hydrazine hydrate; pyridinium chlorochromate; In tetrahydrofuran; methanol; ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmcl.2007.04.092