trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester
CAS No.:184368-70-5
Molecular Formula:C₁₂H₂₁NO₃
Molecular Weight:227.304
Hs Code.:2933399990
European Community (EC) Number:812-427-7
Wikidata:Q76415455
Mol file:184368-70-5.mol

Synonyms:184368-70-5;1821774-86-0;(2R,6R)-rel-tert-Butyl 2,6-dimethyl-4-oxopiperidine-1-carboxylate;tert-butyl (2R,6R)-2,6-dimethyl-4-oxopiperidine-1-carboxylate;trans-2,6-dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester;rel-tert-Butyl (2R,6R)-2,6-dimethyl-4-oxopiperidine-1-carboxylate;N-t-BOC-trans-2,6-Dimethyl-4-Oxopiperidine;MFCD19230166;SCHEMBL16338682;MFCD22377542;AS-0804;AS-83494;N-Boc-trans-2,6-Dimethyl-4-oxopiperidine;CS-0140256;N-t-BOC-trans-2,6-Dimethyl-4-Oxopiperidine, AldrichCPR;TRANS-TERT-BUTYL 2,6-DIMETHYL-4-OXOPIPERIDINE-1-CARBOXYLATE;(2R,6R)-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid t-butyl ester;(2R,6R)-2,6-Dimethyl-4-oxo-piperidine-1-carboxylicacidtert-butylester;(2r,6r)-2,6-dimethyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester;1-Piperidinecarboxylic acid, 2,6-dimethyl-4-oxo-, 1,1-dimethylethylester, trans-

Suppliers and Price of trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2R,6R)-Rel-2,6-dimethyl-4-oxo-1,1-dimethylethylEster1-PiperidineCarboxylicAcid
10mg
$ 45.00

TRC
(2R,6R)-Rel-2,6-dimethyl-4-oxo-1,1-dimethylethylEster1-PiperidineCarboxylicAcid
100mg
$ 310.00

SynQuest Laboratories
N-Boc-trans-2,6-dimethyl-4-oxopiperidine
1 g
$ 815.00

J&W Pharmlab
trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylicacidtert-butylester 98%
1g
$ 698.00

Crysdot
(2R,6R)-rel-tert-Butyl2,6-dimethyl-4-oxopiperidine-1-carboxylate 95+%
250mg
$ 246.00

Crysdot
(2R,6R)-rel-tert-Butyl2,6-dimethyl-4-oxopiperidine-1-carboxylate 95+%
1g
$ 614.00

Biosynth Carbosynth
N-Boc-trans-2,6-dimethyl-4-oxopiperidine
500 mg
$ 600.00

Biosynth Carbosynth
N-Boc-trans-2,6-dimethyl-4-oxopiperidine
1 g
$ 900.00

Biosynth Carbosynth
N-Boc-trans-2,6-dimethyl-4-oxopiperidine
10 g
$ 3300.00

Biosynth Carbosynth
N-Boc-trans-2,6-dimethyl-4-oxopiperidine
5 g
$ 2200.00

Total 8 raw suppliers

Chemical Property of trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

Chemical Property:

Boiling Point:308.2±35.0 °C(Predicted)
PKA:-1.46±0.60(Predicted)
Density:1.027±0.06 g/cm3(Predicted)
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:227.15214353
Heavy Atom Count:16
Complexity:279

Purity/Quality:

97% ^*data from raw suppliers

(2R,6R)-Rel-2,6-dimethyl-4-oxo-1,1-dimethylethylEster1-PiperidineCarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CC(=O)CC(N1C(=O)OC(C)(C)C)C
Isomeric SMILES:C[C@@H]1CC(=O)C[C@H](N1C(=O)OC(C)(C)C)C
Uses (2R,6R)-Rel-2,6-dimethyl-4-oxo-1,1-dimethylethyl Ester 1-Piperidine Carboxylic Acid is a reagent in the preparation of some methylated analogs of isoguvacine derivatives which are potential GABAA agonists.

Technology Process of trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester

There total 19 articles about trans-2,6-Dimethyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%