(-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Base Information

Chemical Name:(-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-
CAS No.:123292-05-7
Molecular Formula:C₃₇H₄₀Br₂O₄
Molecular Weight:708.53
Hs Code.:

(-)-18,14-metheno-6H,14H-dibenzo<f,m><1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Synonyms:

Suppliers and Price of (-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

There total 24 articles about (-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 123292-04-6,123356-74-1
(-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-methanol, 19-ethoxy-10-<2-ethoxy-3-(hydroxymethyl)-5-methylphenyl>-7,8-dihydro-2,12,16-trimethyl-

: 123292-05-7,123356-75-2
(+)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Guidance literature:: With phosphorus tribromide; In benzene; at 25 ℃; for 3h;
DOI:10.1021/jo00284a018

Reference yield:

: 123292-04-6,123356-74-1
(+)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin-4-methanol, 19-ethoxy-10-<2-ethoxy-3-(hydroxymethyl)-5-methylphenyl>-7,8-dihydro-2,12,16-trimethyl-

: 123292-05-7,123356-75-2
(-)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Guidance literature:: With phosphorus tribromide; In benzene; at 25 ℃; for 3h;
DOI:10.1021/jo00284a018

Reference yield:

: 71128-89-7
2,2',2''-trihydroxy-5,5',5''-trimethyl-m-terphenyl

: 123292-05-7,123356-75-2
(+)-18,14-metheno-6H,14H-dibenzo<1,5>dioxacyclotetradecin, 4-(bromomethyl)-10-<3-(bromomethyl)-2-ethoxy-5-methylphenyl>-19-ethoxy-7,8-dihydro-2,12,16-trimethyl-

Guidance literature:: Multi-step reaction with 12 steps

1: 53 percent / K₂CO₃ / acetone / 192 h / 25 °C

2: 56 percent / Br₂ / CHCl₃ / 25 °C

3: 1.) NaH / 1.) THF, 30 min, 1.5 h, 2.) from -5 to 25 deg C

5: 81 percent / 2 N aq. Na₂CO₃, Pd(PPh₃)4 / benzene; ethanol / 42 h / Heating

6: 95 percent / conc. HCl / CHCl₃; ethanol / 24 h / Ambient temperature

7: 1) hexamethylenetetraamine, 2.) H₂O / 1.) 85-90 deg C, 36 h, 2.) 60 deg C, 3 h

8: 45 percent / Cs₂CO₃ / dimethylformamide / 3 h / 50 °C

9: p-toluenesulfonic acid monohydrate / toluene / 36 h / Heating

10: 90 percent / 3 N HCl / aq. ethanol / 2 h / Heating

11: 92 percent / NaBH₄ / ethanol / 12 h

12: 83 percent / PBr₃ / benzene / 3 h / 25 °C

With hydrogenchloride; sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; hexamethylenetetramine; water; bromine; phosphorus tribromide; sodium hydride; sodium carbonate; potassium carbonate; caesium carbonate; toluene-4-sulfonic acid; In ethanol; chloroform; N,N-dimethyl-formamide; acetone; toluene; benzene;
DOI:10.1021/jo00284a018