4-Nitro-2,5-di-t-butylacetanilid

Base Information

• Chemical Name: 4-Nitro-2,5-di-t-butylacetanilid
• CAS No.: 22161-99-5
• Molecular Formula: C₁₆H₂₄N₂O₃
• Molecular Weight: 292.378
• Mol file: 22161-99-5.mol

Synonyms:

Chemical Property of 4-Nitro-2,5-di-t-butylacetanilid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Nitro-2,5-di-t-butylacetanilid

There total 2 articles about 4-Nitro-2,5-di-t-butylacetanilid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,5-di-tert-butyl-phenyl)-acetamide (23278-20-8) → 4-Nitro-2,5-di-t-butylacetanilid (22161-99-5)

Guidance literature:

With nitric acid; In acetic anhydride; acetic acid;

Reference yield:

→ 4-Nitro-2,5-di-t-butylacetanilid (22161-99-5)

Guidance literature:

2,5-Di-t-butylacetanilid, HNO3, H2SO4;

DOI:10.1016/S0040-4020(01)82712-5

Reference yield:

4-Nitro-2,5-di-t-butylacetanilid (22161-99-5) → 5-(tert-butyl)benzene-1,3-diamine (22503-17-9)

Guidance literature:

Multi-step reaction with 5 steps

1: HNO₃

2: H₂SO₄

3: (i) NaNO₂, H₂SO₄, (ii) NaH₂PO₂

4: H₂ / Raney-Ni / propan-2-ol

5: aq. HCl

With hydrogenchloride; sulfuric acid; hydrogen; nitric acid; nickel; In isopropyl alcohol;

upstream raw materials:

N-(2,5-di-tert-butyl-phenyl)-acetamide

Downstream raw materials:

4,6-Dinitro-2,5-di-t-butyl-acetanilid

5-(tert-butyl)benzene-1,3-diamine

2.5-di-tert-butyl-m-phenylenediamine

2-Amino-3,5-dinitro-1,4-di-t-butylbenzol