Technology Process of C22H27N3O2
There total 4 articles about C22H27N3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
membrane-associated γ-aminobutyric acid transporter 1;
In
aq. phosphate buffer; dimethyl sulfoxide;
at 37 ℃;
for 4h;
pH=7.1;
Combinatorial reaction / High throughput screening (HTS);
DOI:10.1002/cmdc.201200201
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
2.1: hydrogenchloride; water / 2 h / 80 °C
2.2: Amberlite IRA-120
3.1: membrane-associated γ-aminobutyric acid transporter 1 / dimethyl sulfoxide; aq. phosphate buffer / 4 h / 37 °C / pH 7.1 / Combinatorial reaction / High throughput screening (HTS)
With
hydrogenchloride; water; trifluoroacetic acid;
In
aq. phosphate buffer; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/cmdc.201200201
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / acetone / 20 h / 20 °C
2.1: triethylamine / ethanol / 1 h / Reflux
3.1: trifluoroacetic acid / dichloromethane / 1 h / 20 °C
4.1: hydrogenchloride; water / 2 h / 80 °C
4.2: Amberlite IRA-120
5.1: membrane-associated γ-aminobutyric acid transporter 1 / dimethyl sulfoxide; aq. phosphate buffer / 4 h / 37 °C / pH 7.1 / Combinatorial reaction / High throughput screening (HTS)
With
hydrogenchloride; water; potassium carbonate; triethylamine; trifluoroacetic acid;
In
aq. phosphate buffer; ethanol; dichloromethane; dimethyl sulfoxide; acetone;
DOI:10.1002/cmdc.201200201