2-[(Tributylsilyl)oxy]phenol

Base Information

• Chemical Name: 2-[(Tributylsilyl)oxy]phenol
• CAS No.: 101541-83-7
• Molecular Formula: C18H32O2Si
• Molecular Weight: 308.536
• DSSTox Substance ID: DTXSID70545211
• Wikidata: Q82422631
• Mol file: 101541-83-7.mol

Synonyms:2-[(Tributylsilyl)oxy]phenol;101541-83-7;SCHEMBL10565767;DTXSID70545211

Chemical Property of 2-[(Tributylsilyl)oxy]phenol

Chemical Property:

• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 11
• Exact Mass: 308.217156794
• Heavy Atom Count: 21
• Complexity: 236

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Si](CCCC)(CCCC)OC1=CC=CC=C1O

Technology Process of 2-[(Tributylsilyl)oxy]phenol

There total 5 articles about 2-[(Tributylsilyl)oxy]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C15H33NO6*2C4H9BrMg + sodiumtris(benzene-1,2 diolato)silicate (101519-12-4) → tri-nBu-(2-hydroxyphenoxy)silane (101541-83-7)

Guidance literature:

In diethyl ether; at 20 ℃; for 5h; further carbonyl compounds, further Grignard/TDA-1 complexes, further solvents;

DOI:10.1016/0040-4020(89)80044-4

Reference yield: 82.0%

→ tri-nBu-(2-hydroxyphenoxy)silane (101541-83-7)

Guidance literature:

Reference yield: 17.0%

n-butyl magnesium bromide (693-03-8) + Cobalt tris(benzene-1,2-diolato)silicate (125916-15-6) → silica gel (112926-00-8,7631-86-9) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + tri-nBu-(2-hydroxyphenoxy)silane (101541-83-7)

Guidance literature:

In tetrahydrofuran; addn. of Grignard reagent to Co compound (36 h, N2, Schlenk tube on a vac. line); hydrolysis with aq. H2SO4;

upstream raw materials:

n-butyl magnesium bromide

Cobalt tris(benzene-1,2-diolato)silicate

sodiumtris(benzene-1,2 diolato)silicate