14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside

Base Information

• Chemical Name: 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside
• CAS No.: 1393730-56-7
• Molecular Formula: C₄₇H₇₄O₁₅
• Molecular Weight: 879.096
• Mol file: 1393730-56-7.mol

Synonyms:

Chemical Property of 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside

There total 19 articles about 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3β-O-(2,4-di-O-acetyl-β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside (1393730-54-5) → 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside (1393730-56-7,384329-61-7)

Guidance literature:

With potassium hydroxide; In methanol; benzene; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c2cc34404a

Reference yield:

3β-hydroxy-12β-tigloyl-14β-hydroxy-pregn-5-en-20-one → 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside (1393730-56-7,384329-61-7)

Guidance literature:

Multi-step reaction with 4 steps

1: triphenylphosphinegold(I) triflate / dichloromethane / 4 h / 20 °C / Molecular sieve; Inert atmosphere

2: sodium carbonate / methanol / 5 h / 20 °C / Inert atmosphere

3: triphenylphosphinegold(I) triflate / toluene / 4 h / -40 °C / Molecular sieve; Inert atmosphere

4: potassium hydroxide / methanol; benzene / 0.5 h / 20 °C / Inert atmosphere

With triphenylphosphinegold(I) triflate; sodium carbonate; potassium hydroxide; In methanol; dichloromethane; toluene; benzene;

DOI:10.1039/c2cc34404a

Reference yield:

3β-O-(β-D-cymaropyranoside)-14β-hydroxy-pregn-5-ene-12β-tigloyl-20-one (957217-39-9) → 14β-hydroxypregn-5-ene-12β-tigloyl-20-one-3-O-(β-D-thevetopyranosyl)-(1->4)-α-D-cymaropyranosyl-(1->4)-β-D-cymaropyranoside (1393730-56-7,384329-61-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphinegold(I) triflate / toluene / 4 h / -40 °C / Molecular sieve; Inert atmosphere

2: potassium hydroxide / methanol; benzene / 0.5 h / 20 °C / Inert atmosphere

With triphenylphosphinegold(I) triflate; potassium hydroxide; In methanol; toluene; benzene;

DOI:10.1039/c2cc34404a

upstream raw materials:

3β-O-(β-D-cymaropyranoside)-14β-hydroxy-pregn-5-ene-12β-tigloyl-20-one

20,20-ethylenedioxy-14β-hydroxy-3-oxo-5β-pregn-12β-acetate

20,20-ethylenedioxy-14β-hydroxy-3-oxopregn-4-ene-12β-acetate

20,20-ethylenedioxypregn-5-ene-3β,12β,14β-triol