1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Base Information

Chemical Name:1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine
CAS No.:180300-61-2
Molecular Formula:C₃₂H₂₇N₃O₈
Molecular Weight:581.582
Hs Code.:

Synonyms:

Suppliers and Price of 1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

There total 9 articles about 1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103931-45-9
5-O-(tert-butyldimethylsilyl)-1,2-O-isopropylidene-α-D-erythro-pentofuranos-3-ulose

: 180300-61-2
1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Guidance literature:: Multi-step reaction with 8 steps

1: 64 percent / tetrahydrofuran / 2 h / -15 °C

2: tetrabutylammonium fluoride / tetrahydrofuran / 0.33 h / Ambient temperature

3: pyridine / 4 h / Ambient temperature

4: aq. HCl / tetrahydrofuran / 8 h / Heating

5: DMAP / pyridine / 24 h / 100 °C

6: 1.) (NH₄)2SO₄, hexamethyldisilazane, 2.) trimethylsilyl triflate / 2.) CH₃CN, RT, 39 h

7: Et₃N, DMAP / acetonitrile / Ambient temperature

8: 28percent NH₄OH / 2.5 h / Ambient temperature

With hydrogenchloride; dmap; ammonium sulfate; ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; tetrabutyl ammonium fluoride; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; pyridine; acetonitrile;
DOI:10.1021/jm9801814

Reference yield:

: Benzoic acid (2R,3S,4R)-3,4,5-trihydroxy-3-vinyl-tetrahydro-furan-2-ylmethyl ester

: 180300-61-2
1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Guidance literature:: Multi-step reaction with 4 steps

1: DMAP / pyridine / 24 h / 100 °C

2: 1.) (NH₄)2SO₄, hexamethyldisilazane, 2.) trimethylsilyl triflate / 2.) CH₃CN, RT, 39 h

3: Et₃N, DMAP / acetonitrile / Ambient temperature

4: 28percent NH₄OH / 2.5 h / Ambient temperature

With dmap; ammonium sulfate; ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; In pyridine; acetonitrile;
DOI:10.1021/jm9801814

Reference yield:

: 180300-90-7
((3aR,5R,6R,6aR)-6-hydroxy-2,2-dimethyl-6-vinyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate

: 180300-61-2
1-(2,3,5-tri-O-benzoyl-3-C-ethenyl-β-D-ribofuranosyl)cytosine

Guidance literature:: Multi-step reaction with 5 steps

1: aq. HCl / tetrahydrofuran / 8 h / Heating

2: DMAP / pyridine / 24 h / 100 °C

3: 1.) (NH₄)2SO₄, hexamethyldisilazane, 2.) trimethylsilyl triflate / 2.) CH₃CN, RT, 39 h

4: Et₃N, DMAP / acetonitrile / Ambient temperature

5: 28percent NH₄OH / 2.5 h / Ambient temperature

With hydrogenchloride; dmap; ammonium sulfate; ammonium hydroxide; trimethylsilyl trifluoromethanesulfonate; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; In tetrahydrofuran; pyridine; acetonitrile;
DOI:10.1021/jm9801814