Technology Process of C16H18N6O
There total 6 articles about C16H18N6O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; ammonium chloride; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
DOI:10.1039/c6md00560h
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; caesium carbonate / N,N-dimethyl acetamide / 4 h / 100 °C / Inert atmosphere; Sealed tube
2: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C
3: ammonium chloride; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; 4-methyl-morpholine / N,N-dimethyl-formamide / 1 h
With
4-methyl-morpholine; hydrogenchloride; tris-(dibenzylideneacetone)dipalladium(0); ammonium chloride; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
1,4-dioxane; N,N-dimethyl acetamide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogenchloride / 1,4-dioxane / 2 h / 20 °C
2: ammonium chloride; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; 4-methyl-morpholine / N,N-dimethyl-formamide / 1 h
With
4-methyl-morpholine; hydrogenchloride; ammonium chloride; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
1,4-dioxane; N,N-dimethyl-formamide;