Technology Process of (1S,2R)-2,3-dihydro-2-(hydroxymethyl)-2,6-dimethyl-1H-inden-1-yl 4-nitrobenzoate
There total 6 articles about (1S,2R)-2,3-dihydro-2-(hydroxymethyl)-2,6-dimethyl-1H-inden-1-yl 4-nitrobenzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridinium p-toluenesulfonate;
In
methanol;
at 20 ℃;
DOI:10.1039/c1ob06545a
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Geotrichum candidum (NBRC 5767) / ethanol / 30 °C / pH 5.6 / potato sucrose liquid medium; Enzymatic reaction
2: 1H-imidazole; dmap / 20 °C
3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 20 °C
4: pyridinium p-toluenesulfonate / methanol / 20 °C
With
1H-imidazole; dmap; pyridinium p-toluenesulfonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol; ethanol;
DOI:10.1039/c1ob06545a
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Burkholderia cepacia lipase-PS / Enzymatic reaction
2: porcine pancreatic lipase / Enzymatic reaction
3: Geotrichum candidum (NBRC 5767) / ethanol / 30 °C / pH 5.6 / potato sucrose liquid medium; Enzymatic reaction
4: 1H-imidazole; dmap / 20 °C
5: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 20 °C
6: pyridinium p-toluenesulfonate / methanol / 20 °C
With
1H-imidazole; dmap; pyridinium p-toluenesulfonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol; ethanol;
DOI:10.1039/c1ob06545a
