2-Phenyl-3-benzylquinoxaline

Base Information

• Chemical Name: 2-Phenyl-3-benzylquinoxaline
• CAS No.: 10173-29-2
• Molecular Formula: C21H16N2
• Molecular Weight: 296.371
• Hs Code.: 2933990090
• Mol file: 10173-29-2.mol

Synonyms:2-Benzyl-3-phenyl-chinoxalin;2-benzyl-3-phenyl-quinoxaline;Quinoxaline,2-benzyl-3-phenyl;Quinoxaline,2-phenyl-3-(phenylmethyl);2-Phenyl-3-benzylquinoxaline;

Chemical Property of 2-Phenyl-3-benzylquinoxaline

Chemical Property:

• PSA: 25.78000
• LogP: 4.88760

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Phenyl-3-benzylquinoxaline

There total 12 articles about 2-Phenyl-3-benzylquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

chalcone epoxide (5411-12-1) + 1,2-diamino-benzene (95-54-5) → 2-benzyl-3-phenylquinoxaline (10173-29-2)

Guidance literature:

With caesium carbonate; In ethylene glycol; at 120 ℃; for 0.266667h; Reagent/catalyst; Solvent; Temperature; Microwave irradiation; Green chemistry;

DOI:10.1002/jhet.2128

Reference yield: 80.0%

1,1a-dihydro-1,2-diphenylazirino<1,2-a>quinoxaline (18039-32-2,117836-44-9) → 2-benzyl-3-phenylquinoxaline (10173-29-2)

Guidance literature:

With hydrogenchloride; In acetone; Heating;

DOI:10.1007/BF00475321

Reference yield: 80.0%

2-benzyl-3-phenylquinoxaline 1,4-dioxide (53326-80-0) → 2-benzyl-3-phenylquinoxaline (10173-29-2)

Guidance literature:

With diphosphorus tetraiodide; In chloroform; for 24h; Ambient temperature;

upstream raw materials:

1,3-diphenylpropane-1,2-dione

1,2-diamino-benzene

2-hydroxychalcone

1,1a-dihydro-1,2-diphenylazirino<1,2-a>quinoxaline

Downstream raw materials:

acetoxy-phenyl-(3-phenyl-quinoxalin-2-yl)-methane

Refernces

• 1、 Chen, Tengfei,Chen, Xun,Wei, Jun,Lin, Dongen,Xie, Ying,Zeng, Wei. "Copper-Catalyzed Cascade Cycloamination of α-Csp3-H Bond of N-Aryl Ketimines with Azides: Access to Quinoxalines". supporting information. p. 2078 - 2081. Retrieved 2016/06/01.
• 2、 Despinoy, Christophe,Lloyd, Douglas,McNab, Hamish,Reed, David. "Flash vacuum pyrolysis of 1,5-benzodiazepines". . p. 9667 - 9676. Retrieved 2007/10/03.