Benzene, (cyclopentylsulfinyl)-

Base Information

• Chemical Name: Benzene, (cyclopentylsulfinyl)-
• CAS No.: 10181-73-4
• Molecular Formula: C11H14OS
• Molecular Weight: 194.298
• DSSTox Substance ID: DTXSID70473101
• Nikkaji Number: J604.273B
• Mol file: 10181-73-4.mol

Synonyms:10181-73-4;Benzene, (cyclopentylsulfinyl)-;SCHEMBL777646;DTXSID70473101

Chemical Property of Benzene, (cyclopentylsulfinyl)-

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 194.07653624
• Heavy Atom Count: 13
• Complexity: 179

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)S(=O)C2=CC=CC=C2

Technology Process of Benzene, (cyclopentylsulfinyl)-

There total 4 articles about Benzene, (cyclopentylsulfinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cyclopentyl phenyl sulfide (19744-72-0) → (phenylsulfinyl)cyclopentane (10181-73-4)

Guidance literature:

With sodium periodate; In methanol; for 18h; Ambient temperature;

DOI:10.1021/jo00214a031

Reference yield:

cyclopentylthiol (1679-07-8) → (phenylsulfinyl)cyclopentane (10181-73-4)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / dichloromethane / 20 h / 20 °C / Inert atmosphere

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C / Inert atmosphere

3: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / toluene / 12 h / 80 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium carbonate; caesium carbonate; 3-chloro-benzenecarboperoxoic acid; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In dichloromethane; toluene; 1: |Michael Addition;

DOI:10.1021/jacs.8b00178

Reference yield:

C12H22O2S → (phenylsulfinyl)cyclopentane (10181-73-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1 h / 0 °C / Inert atmosphere

2: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / toluene / 12 h / 80 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 3-chloro-benzenecarboperoxoic acid; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In dichloromethane; toluene;

DOI:10.1021/jacs.8b00178

upstream raw materials:

cyclopentyl phenyl sulfide

thiophenol

cyclopentylthiol

Downstream raw materials:

cyclopent-1-en-1-yl (phenyl) sulfide

1-(phenylthio)-2-(trifluoroacetyl)cyclopentene

S-Cyclopentyl-S-phenyl-N-(p-tolylsulfonyl)sulfoximin

cyclopentyl phenyl sulfide