C₂₁H₁₆ClN₃O₂

Base Information

Chemical Name:C₂₁H₁₆ClN₃O₂
CAS No.:1186038-00-5
Molecular Formula:C₂₁H₁₆ClN₃O₂
Molecular Weight:377.83
Hs Code.:

C<sub>21</sub>H<sub>16</sub>ClN<sub>3</sub>O<sub>2</sub>

Synonyms:

Suppliers and Price of C₂₁H₁₆ClN₃O₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₂₁H₁₆ClN₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₂₁H₁₆ClN₃O₂

There total 7 articles about C₂₁H₁₆ClN₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₁H₂₇N₃O₃

: 1186038-00-5
C₂₁H₁₆ClN₃O₂

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hexamethyldisilazane / tetrahydrofuran / 20 °C / Inert atmosphere

2: trichlorophosphate / 120 °C

3: 1-methyl-pyrrolidin-2-one / 120 °C / Microwave irradiation

With 1-methyl-pyrrolidin-2-one; sodium hexamethyldisilazane; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/jm101251q

Reference yield:

: 1975-52-6
5-nitro-o-toluic acid

: 1186038-00-5
C₂₁H₁₆ClN₃O₂

Guidance literature:: Multi-step reaction with 7 steps

1: sulfuric acid / Reflux

2: palladium 10% on activated carbon; hydrogen / methanol / Inert atmosphere

3: N-iodo-succinimide; acetic acid / 1.5 h / 20 °C

4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / 1,4-dioxane; water / Inert atmosphere; Reflux

5: sodium hexamethyldisilazane / tetrahydrofuran / 20 °C / Inert atmosphere

6: trichlorophosphate / 120 °C

7: 1-methyl-pyrrolidin-2-one / 120 °C / Microwave irradiation

With 1-methyl-pyrrolidin-2-one; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; N-iodo-succinimide; sulfuric acid; palladium 10% on activated carbon; hydrogen; sodium hexamethyldisilazane; caesium carbonate; acetic acid; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; methanol; water; 4: Suzuki coupling;
DOI:10.1021/jm101251q

Reference yield:

: 77324-87-9
methyl 2-methyl-5-nitrobenzoate

: 1186038-00-5
C₂₁H₁₆ClN₃O₂

Guidance literature:: Multi-step reaction with 6 steps

1: palladium 10% on activated carbon; hydrogen / methanol / Inert atmosphere

2: N-iodo-succinimide; acetic acid / 1.5 h / 20 °C

3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate / 1,4-dioxane; water / Inert atmosphere; Reflux

4: sodium hexamethyldisilazane / tetrahydrofuran / 20 °C / Inert atmosphere

5: trichlorophosphate / 120 °C

6: 1-methyl-pyrrolidin-2-one / 120 °C / Microwave irradiation

With 1-methyl-pyrrolidin-2-one; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; N-iodo-succinimide; palladium 10% on activated carbon; hydrogen; sodium hexamethyldisilazane; caesium carbonate; acetic acid; trichlorophosphate; In tetrahydrofuran; 1,4-dioxane; methanol; water; 3: Suzuki coupling;
DOI:10.1021/jm101251q