4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline

Base Information

Chemical Name:4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline
CAS No.:10185-71-4
Molecular Formula:C10H11N3O
Molecular Weight:189.217
Hs Code.:
European Community (EC) Number:831-769-8
DSSTox Substance ID:DTXSID50462957
Wikidata:Q82287624
Mol file:10185-71-4.mol

Synonyms:4-(5-ethyl-1,2,4-oxadiazol-3-yl)aniline;10185-71-4;Benzenamine, 4-(5-ethyl-1,2,4-oxadiazol-3-yl)-;SCHEMBL5311162;DTXSID50462957;GBCCZEVTBFBSTB-UHFFFAOYSA-N;MFCD12191340;AKOS004912150;CS-0439879;4-(5-ethyl-[1,2,4]oxadiazol-3-yl)-phenylamine

Suppliers and Price of 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:189.090211983
Heavy Atom Count:14
Complexity:180

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=NC(=NO1)C2=CC=C(C=C2)N

Technology Process of 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline

There total 5 articles about 4-(5-Ethyl-1,2,4-oxadiazol-3-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 10185-71-4
3-(4'-aminophenyl)-5-ethyl-1,2,4-oxadiazole

Guidance literature:

Reference yield: 70.0%

: 10185-65-6
3-(4-nitrophenyl)-5-ethyl-1,2,4-oxadiazole

: 10185-71-4
3-(4'-aminophenyl)-5-ethyl-1,2,4-oxadiazole

Guidance literature:: With sodium sulfide; In 1,4-dioxane; water; at 80 ℃; for 0.75h; Inert atmosphere;
DOI:10.1016/j.bmc.2014.02.013

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 10185-71-4
3-(4'-aminophenyl)-5-ethyl-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 4 steps

1: hydroxylamine hydrochloride / dimethyl sulfoxide / 3 h / 20 - 100 °C

2: hydroxylamine hydrochloride; sodium hydroxide / water; ethanol / 36 h / Inert atmosphere; Reflux

3: pyridine / 0.5 h / Reflux; Inert atmosphere

4: sodium sulfide / 1,4-dioxane; water / 0.75 h / 80 °C / Inert atmosphere

With pyridine; sodium sulfide; hydroxylamine hydrochloride; sodium hydroxide; In 1,4-dioxane; ethanol; water; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2014.02.013