Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Base Information

• Chemical Name: Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester
• CAS No.: 134737-01-2
• Molecular Formula: C₂₉H₂₈N₆O₈
• Molecular Weight: 588.577
• Mol file: 134737-01-2.mol

Synonyms:

Chemical Property of Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

There total 1 articles about Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[Acetyl-(9H-fluoren-2-yl)-aminooxy]-4-oxo-butyric acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (134756-81-3) → N-Hydroxy-2-acetylaminofluoren (53-95-2) + Succinic acid mono-[(2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl] ester (134756-83-5) + Succinic acid 2-acetylamino-9H-fluoren-3-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (134737-01-2) + Succinic acid 2-acetylamino-9H-fluoren-1-yl ester (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester (134737-00-1) + Succinic acid mono-((2R,3S,5R)-5-{8-[acetyl-(9H-fluoren-2-yl)-amino]-2-amino-6-oxo-1,6-dihydro-purin-9-yl}-3-hydroxy-tetrahydro-furan-2-ylmethyl) ester (134756-82-4)

Guidance literature:

With phosphate buffer; In acetone; at 25 ℃; Rate constant; Product distribution; different ratios of water/acetone;

DOI:10.1021/jo00016a001

upstream raw materials:

4-[Acetyl-(9H-fluoren-2-yl)-aminooxy]-4-oxo-butyric acid (2R,3S,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester