Technology Process of trans-9-methoxy-2,3,4a,5,6,10b-hexahydro-4H-naphth<1,2-b><1,4>oxazin-3-one
There total 8 articles about trans-9-methoxy-2,3,4a,5,6,10b-hexahydro-4H-naphth<1,2-b><1,4>oxazin-3-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
water; isopropyl alcohol;
for 2h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium tert-butoxide, isoamyl nitrite / diethyl ether; butan-1-ol / 4 h / Ambient temperature
2: H2 / 10percent Pd/C / tetrahydrofuran
3: 60 percent / sodium borohydride / ethanol
4: LiAlH4 / tetrahydrofuran; ethane-1,2-diol; dimethyl ether / 1 h / Heating
5: 1.) Na2CO3, 2.) NaH / 1.) ethyl acetate, 1 h, 2.) CH3CN, THF, 1 h
With
sodium tetrahydroborate; lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; sodium hydride; sodium carbonate; isopentyl nitrite;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; Dimethyl ether; ethylene glycol; butan-1-ol;
DOI:10.1021/jm00378a014
- Guidance literature:
-
Multi-step reaction with 4 steps
1: H2 / 10percent Pd/C / tetrahydrofuran
2: 60 percent / sodium borohydride / ethanol
3: LiAlH4 / tetrahydrofuran; ethane-1,2-diol; dimethyl ether / 1 h / Heating
4: 1.) Na2CO3, 2.) NaH / 1.) ethyl acetate, 1 h, 2.) CH3CN, THF, 1 h
With
sodium tetrahydroborate; lithium aluminium tetrahydride; hydrogen; sodium hydride; sodium carbonate;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; Dimethyl ether; ethylene glycol;
DOI:10.1021/jm00378a014
