1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine

Base Information

• Chemical Name: 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine
• CAS No.: 68537-54-2
• Molecular Formula: C₆₁H₆₃N₅O₂₃S
• Molecular Weight: 1266.26
• Mol file: 68537-54-2.mol

Synonyms:

Chemical Property of 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine

There total 1 articles about 1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1L-N1-benzyloxycarbonyl-O6-(2-benzyloxycarbonylamino-O4,O6-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N3,O4-carbonyl-2-deoxy-streptamine (63604-34-2) + methyl O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-ξ-D-ribofuranoside (68537-52-0,68537-59-7) → 1L-N1-benzyloxycarbonyl-O6-(2-benzyloxycarbonylamino-O4,O6-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O5-[O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N3,O4-carbonyl-2-deoxy-streptamine (68537-54-2)

Guidance literature:

Multistep reaction; (i) HCl, CH₂Cl₂, (ii) /BRN= 1068056/, Drierite, Hg(CN)2, (iii) Py, CHCl₃;

DOI:10.7164/antibiotics.31.863

Reference yield:

1L-N1-benzyloxycarbonyl-O6-(2-benzyloxycarbonylamino-O4,O6-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O5-[O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N3,O4-carbonyl-2-deoxy-streptamine (68537-54-2) → 1L-N1-benzyloxycarbonyl-O6-(2-benzyloxycarbonylamino-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O5-[O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N3,O4-carbonyl-2-deoxy-streptamine (68537-55-3)

Guidance literature:

With acetic acid; In 1,4-dioxane;

DOI:10.7164/antibiotics.31.863

Reference yield:

1L-N1-benzyloxycarbonyl-O6-(2-benzyloxycarbonylamino-O4,O6-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O5-[O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N3,O4-carbonyl-2-deoxy-streptamine (68537-54-2) → 1L-N1-benzyloxycarbonyl-O6-[2-benzyloxycarbonylamino-O6-(toluene-4-sulfonyl)-α-D-ribo-2,3-dideoxy-hexopyranosyl]-O5-[O2,O3-bis-(4-nitro-benzoyl)-O5-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N3,O4-carbonyl-2-deoxy-streptamine (68537-56-4)

Guidance literature:

Multi-step reaction with 2 steps

1: AcOH / dioxane

2: Py / -10 °C

With pyridine; acetic acid; In 1,4-dioxane;

DOI:10.7164/antibiotics.31.863

upstream raw materials:

1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-O⁴,O⁶-cyclohexane-1,1-diyl-α-D-ribo-2,3-dideoxy-hexopyranosyl)-N³,O⁴-carbonyl-2-deoxy-streptamine

methyl O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-ξ-D-ribofuranoside

Downstream raw materials:

1L-N¹-benzyloxycarbonyl-O⁶-(2-benzyloxycarbonylamino-α-D-ribo-2,3-dideoxy-hexopyranosyl)-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine

1L-N¹-benzyloxycarbonyl-O⁶-[2-benzyloxycarbonylamino-O⁶-(toluene-4-sulfonyl)-α-D-ribo-2,3-dideoxy-hexopyranosyl]-O⁵-[O²,O³-bis-(4-nitro-benzoyl)-O⁵-(toluene-4-sulfonyl)-β-D-xylofuranosyl]-N³,O⁴-carbonyl-2-deoxy-streptamine