Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate

Base Information

Chemical Name:Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate
CAS No.:107618-22-4
Molecular Formula:C₁₃H₂₀N₄O₂
Molecular Weight:264.327
Hs Code.:
European Community (EC) Number:600-841-9
DSSTox Substance ID:DTXSID101187034

Synonyms:SCHEMBL13319035;DTXSID101187034;Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate;107618-22-4

Suppliers and Price of Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate

Chemical Property:

Vapor Pressure:1.06E-08mmHg at 25°C
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:264.15862589
Heavy Atom Count:19
Complexity:292

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)N1CCC(CC1)NC2=C(C=CC=N2)N

Technology Process of Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate

There total 5 articles about Ethyl 4-[(3-amino-2-pyridinyl)amino]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 618900-69-9
Ethyl 4-(3-nitropyridin-2-ylamino)piperidine-1-carboxylate

: 107618-22-4
ethyl 4-(3-aminopyridin-2-ylamino)piperidine-1-carboxylate

Guidance literature:: With hydrogen; nickel; In ethanol; for 4h; under 2068.65 Torr;

Reference yield:

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 107618-22-4
ethyl 4-(3-aminopyridin-2-ylamino)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: Na₂CO₃, KI / various solvent(s) / 28 h / 160 °C

2: H₂ / Raney Ni / ethanol; tetrahydrofuran / 1 h / Ambient temperature

With hydrogen; sodium carbonate; potassium iodide; nickel; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00388a012

Reference yield:

: 58859-46-4
ethyl 4-aminopiperidine-1-carboxylate

: 107618-22-4
ethyl 4-(3-aminopyridin-2-ylamino)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: Na₂CO₃, KI / various solvent(s) / 28 h / 160 °C

2: H₂ / Raney Ni / ethanol; tetrahydrofuran / 1 h / Ambient temperature

With hydrogen; sodium carbonate; potassium iodide; nickel; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00388a012