3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P¹,P²-bis(2-chlorophenyl) ester

Base Information

• Chemical Name: 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P¹,P²-bis(2-chlorophenyl) ester
• CAS No.: 81691-47-6
• Molecular Formula: C₉₄H₁₁₃Cl₂N₁₅O₂₃P₂Si₄
• Molecular Weight: 2066.21
• Mol file: 81691-47-6.mol

Synonyms:

Chemical Property of 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P¹,P²-bis(2-chlorophenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P¹,P²-bis(2-chlorophenyl) ester

There total 1 articles about 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P¹,P²-bis(2-chlorophenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C66H72ClN10O16PSi2 (81691-49-8) + 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenosine 2'-(2-chlorophenyl) phosphomonotriazolide (81705-89-7) → 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P1,P2-bis(2-chlorophenyl) ester (81691-47-6)

Guidance literature:

With dmap; In tetrahydrofuran; at 37 ℃; for 24h; Yield given;

Reference yield:

3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenylyl-(2'->5')-3'-O-(tetraisopropyldisiloxane-1-yl)adenylyl-(2'->5')-2',3'-di-O-benzoyl-N,N-dibenzoyladenosine P1,P2-bis(2-chlorophenyl) ester (81691-47-6) → adenylyl(2'-5')adenylyl(2'-5')adenosine (70062-83-8)

Guidance literature:

With ammonium hydroxide; tetrabutyl ammonium fluoride; Yield given. Multistep reaction; 1.) dioxane, 60 deg C, 7 h, 2.) THF, 20 deg C, 1 h;

upstream raw materials:

C₆₆H₇₂ClN₁₀O₁₆PSi₂

3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)adenosine 2'-(2-chlorophenyl) phosphomonotriazolide

Downstream raw materials:

adenylyl(2'-5')adenylyl(2'-5')adenosine