Benzene, 1,2-bis(azidomethyl)-

Base Information

• Chemical Name: Benzene, 1,2-bis(azidomethyl)-
• CAS No.: 102437-79-6
• Molecular Formula: C8H8N6
• Molecular Weight: 188.192
• DSSTox Substance ID: DTXSID60446788
• Nikkaji Number: J698.946B
• Wikidata: Q82265514
• Mol file: 102437-79-6.mol

Synonyms:1,2-bis(azidomethyl)benzene;Benzene, 1,2-bis(azidomethyl)-;102437-79-6;bis-(azidomethyl) benzene;DTXSID60446788

Chemical Property of Benzene, 1,2-bis(azidomethyl)-

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 188.08104428
• Heavy Atom Count: 14
• Complexity: 235

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CN=[N+]=[N-])CN=[N+]=[N-]

Technology Process of Benzene, 1,2-bis(azidomethyl)-

There total 6 articles about Benzene, 1,2-bis(azidomethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

α,α'-dibromo-o-xylene (91-13-4) → 1,2-bis(azidomethyl)benzene (102437-79-6)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 5h; Inert atmosphere;

DOI:10.1039/b902905b

Reference yield: 95.0%

o-Xylylene dichloride (612-12-4) → 1,2-bis(azidomethyl)benzene (102437-79-6)

Guidance literature:

With sodium azide; In water; at 120 ℃; for 0.5h; microwave irradiation;

DOI:10.1021/jo061114h

Reference yield: 93.0%

1-(azidomethyl)-2-(bromomethyl)benzene (887144-05-0) → 1,2-bis(azidomethyl)benzene (102437-79-6)

Guidance literature:

With sodium azide; In ethanol; at 20 ℃; for 1.5h; Sealed tube; Green chemistry;

DOI:10.1039/d1gc02002a

upstream raw materials:

o-Xylylene dichloride

α,α'-dibromo-o-xylene

phthalyl alcohol

o-xylene

Downstream raw materials:

1,1'-<1,2-phenylenebis(methylene)>bis(triazole-4,5-dicarboxyaldehyde) tetrakis(ethyl acetal)

tetra-tert-butyl 1,1'-(o-phenylenedimethylene)bis<1H-1,2,3-triazole-4,5-dicarboxylate>

α,α'-Bis(methyltriazeno)-o-xylene

1,1'-(p-phenylenedimethylene)bis<4-phenyl-1H-1,2,3-triazole>