5S,6R-6-epi-Leukotriene A₄

Base Information

Chemical Name:5S,6R-6-epi-Leukotriene A₄
CAS No.:114129-56-5
Molecular Formula:C₂₀H₃₀O₃
Molecular Weight:318.456
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5S,6R-6-epi-Leukotriene A₄

Chemical Property:

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Technology Process of 5S,6R-6-epi-Leukotriene A₄

There total 15 articles about 5S,6R-6-epi-Leukotriene A₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 74448-21-8,74497-08-8,81075-82-3,81075-83-4,118333-86-1,118333-88-3
rac-trans-(2E,4E)-3-(1,3-tetradecadiene-5,8-diynyl)oxiranebutanoic acid methyl ester

: 71548-17-9,72059-45-1,74497-09-9,76375-76-3,77341-35-6,114129-55-4,114129-56-5,114129-57-6
(+/-)-LTA

Guidance literature:: With hydrogen; Lindlar's catalyst; In hexane;
DOI:10.1021/ja00536a066

Reference yield:

: C₂₀H₃₂O₄

: 126432-17-5,106154-18-1
5‐oxo‐6,8,11,14‐eicosatetraenoic acid

: 114129-56-5
5S,6R-6-epi-Leukotriene A₄

Guidance literature:: With recombinant Arabidopsis thaliana At-lipoxygenase1; In aq. buffer; at 0 ℃; for 0.025h; pH=6.0; Inert atmosphere; Enzymatic reaction;
DOI:10.1194/jlr.M033746

Reference yield:

: C₂₁H₃₄O₄

: 126432-17-5,106154-18-1
5‐oxo‐6,8,11,14‐eicosatetraenoic acid

: 114129-56-5
5S,6R-6-epi-Leukotriene A₄

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / methanol; dichloromethane / 0.33 h / 20 °C / Inert atmosphere; Sonication; Heating

2: recombinant Arabidopsis thaliana At-lipoxygenase1 / aq. buffer / 0.03 h / 0 °C / pH 6.0 / Inert atmosphere; Enzymatic reaction

With recombinant Arabidopsis thaliana At-lipoxygenase1; potassium hydroxide; In methanol; dichloromethane;
DOI:10.1194/jlr.M033746