C₁₃H₁₇FO

Base Information

• Chemical Name: C₁₃H₁₇FO
• CAS No.: 1415315-16-0
• Molecular Formula: C₁₃H₁₇FO
• Molecular Weight: 208.276
• Mol file: 1415315-16-0.mol

Synonyms:

Chemical Property of C₁₃H₁₇FO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₇FO

There total 3 articles about C₁₃H₁₇FO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C11H12BrFO + ethylmagnesium bromide (925-90-6) → C13H17FO (1415315-16-0) + C13H17FO

Guidance literature:

With C₃₇H₃₅N₂O⁽¹⁺⁾*Cl^(1-); In diethyl ether; at -15 ℃; Overall yield = 53 %; enantioselective reaction; Inert atmosphere;

DOI:10.1039/c2cc36513h

Reference yield:

C11H13FO2 → C13H17FO (1415315-16-0) + C13H17FO

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine; carbon tetrabromide / acetonitrile / 1 h / 0 - 20 °C

2: C₃₇H₃₅N₂O⁽¹⁺⁾*Cl^(1-) / diethyl ether / -15 °C / Inert atmosphere

With carbon tetrabromide; C₃₇H₃₅N₂O⁽¹⁺⁾*Cl^(1-); triphenylphosphine; In diethyl ether; acetonitrile;

DOI:10.1039/c2cc36513h

Reference yield:

ethyl 3-(3'-methoxyphenyl)-4-fluoro-2-butenoate (85465-51-6) → C13H17FO (1415315-16-0) + C13H17FO

Guidance literature:

Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / toluene; hexane / 1 h / -78 - 0 °C

2: triphenylphosphine; carbon tetrabromide / acetonitrile / 1 h / 0 - 20 °C

3: C₃₇H₃₅N₂O⁽¹⁺⁾*Cl^(1-) / diethyl ether / -15 °C / Inert atmosphere

With carbon tetrabromide; C₃₇H₃₅N₂O⁽¹⁺⁾*Cl^(1-); diisobutylaluminium hydride; triphenylphosphine; In diethyl ether; hexane; toluene; acetonitrile;

DOI:10.1039/c2cc36513h

upstream raw materials:

ethylmagnesium bromide

ethyl 3-(3'-methoxyphenyl)-4-fluoro-2-butenoate