Pravastatin 6'-Ketone SodiuM Salt

Base Information

• Chemical Name: Pravastatin 6'-Ketone SodiuM Salt
• CAS No.: 201423-59-8
• Molecular Formula: C₂₃H₃₄O₇
• Molecular Weight: 422.519
• Mol file: 201423-59-8.mol

Synonyms:

Chemical Property of Pravastatin 6'-Ketone SodiuM Salt

Chemical Property:

• Melting Point: >80°C (dec.)
• Storage Temp.: Hygroscopic, -86°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:

Pravastatin6''-KetoneSodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Pravastatin 6''-Ketone Sodium Salt is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of HMG-CoA reductase. It can be used as a drug to for lowering cholesterol and preventing cardiovascular disease.

Technology Process of Pravastatin 6'-Ketone SodiuM Salt

There total 1 articles about Pravastatin 6'-Ketone SodiuM Salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-oxo-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester → R-195 (136590-28-8) + R-104 (201423-59-8)

Guidance literature:

With sodium hydroxide; In acetonitrile; at 0 ℃; for 0.25h;

DOI:10.1248/bpb.20.1199

Refernces