-4-Brom-2,2-diphenylbutyronitril

Base Information

• Chemical Name: -4-Brom-2,2-diphenylbutyronitril
• CAS No.: 73472-57-8
• Molecular Formula: C₁₆H₁₄BrN
• Molecular Weight: 304.166
• Mol file: 73472-57-8.mol

Synonyms:

Chemical Property of -4-Brom-2,2-diphenylbutyronitril

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of -4-Brom-2,2-diphenylbutyronitril

There total 2 articles about -4-Brom-2,2-diphenylbutyronitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dibromoethane-d4 (22581-63-1) + Diphenylacetonitrile (86-29-3) → -4-Brom-2,2-diphenylbutyronitril (73472-57-8)

Guidance literature:

With sodium hydroxide; dibenzo-18-crown-6;

DOI:10.1248/cpb.50.1137

Reference yield:

→ -4-Brom-2,2-diphenylbutyronitril (73472-57-8)

Guidance literature:

Diphenylacetonitril, d(4)-1,2-Dibromethan;

DOI:10.1002/jlcr.2580160513

Reference yield:

-4-Brom-2,2-diphenylbutyronitril (73472-57-8) → D4-KRP-197 (499996-95-1)

Guidance literature:

Multi-step reaction with 2 steps

1: TEA / dimethylformamide

2: KOH / propan-2-ol

With potassium hydroxide; TEA; In N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1248/cpb.50.1137

upstream raw materials:

1,2-dibromoethane-d4

Diphenylacetonitrile

Downstream raw materials:

D₄-KRP-197