methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Base Information

Chemical Name:methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt
CAS No.:1080009-78-4
Molecular Formula:C₄H₄O₄*C₃₁H₄₀N₆O₃
Molecular Weight:660.77
Hs Code.:

methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Synonyms:

Suppliers and Price of methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

There total 8 articles about methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1080007-17-5
methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate

: 110-17-8,26099-09-2
(2E)-but-2-enedioic acid

: 1080009-78-4
methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Guidance literature:: In methanol; for 0.333333h;

Reference yield:

: 860173-10-0
tert-butyl {3-[(3-nitroquinolin-4-yl)amino]propyl}carbamate

: 1080009-78-4
methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Guidance literature:: Multi-step reaction with 8 steps

1.1: hydrogen / 1% platinum on charcoal / tetrahydrofuran / 72 h / 20 °C / 2250.23 Torr

2.1: 1-methyl-pyrrolidin-2-one / 73.5 h / 20 - 80 °C

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 5 - 20 °C

4.1: ammonia; p-toluenesulfonyl chloride / dichloromethane; water / 2 h / 0 - 20 °C

5.1: trifluoroacetic acid / dichloromethane / 0.33 h

6.1: tetrahydrofuran / 16 h

6.2: 1 h

7.1: triethylamine / dichloromethane; N,N-dimethyl-formamide / 88 h

8.1: methanol / 0.33 h

With ammonia; hydrogen; triethylamine; p-toluenesulfonyl chloride; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; 1% platinum on charcoal; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 611-36-9
quinolin-4-ol

: 1080009-78-4
methyl 2-(4-((N-(3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl)-2-(dimethylamino)acetamido)methyl)phenyl)acetate fumaric acid salt

Guidance literature:: Multi-step reaction with 10 steps

1.1: nitric acid; propionic acid / 1.75 h / 125 °C / Heating / reflux

2.1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 2.5 h / Heating / reflux

2.2: 0 °C

3.1: hydrogen / 1% platinum on charcoal / tetrahydrofuran / 72 h / 20 °C / 2250.23 Torr

4.1: 1-methyl-pyrrolidin-2-one / 73.5 h / 20 - 80 °C

5.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 5 - 20 °C

6.1: ammonia; p-toluenesulfonyl chloride / dichloromethane; water / 2 h / 0 - 20 °C

7.1: trifluoroacetic acid / dichloromethane / 0.33 h

8.1: tetrahydrofuran / 16 h

8.2: 1 h

9.1: triethylamine / dichloromethane; N,N-dimethyl-formamide / 88 h

10.1: methanol / 0.33 h

With thionyl chloride; ammonia; hydrogen; nitric acid; propionic acid; triethylamine; p-toluenesulfonyl chloride; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; 1% platinum on charcoal; N,N-dimethyl-formamide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; methanol; dichloromethane; water; N,N-dimethyl-formamide;