Technology Process of Isoproturon-didemethyl
There total 5 articles about Isoproturon-didemethyl which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
water;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1039/c8ra03761b
- Guidance literature:
-
With
ammonium hydroxide;
In
water; N,N-dimethyl-formamide; toluene;
at 90 ℃;
Inert atmosphere;
DOI:10.1021/acs.joc.9b01697
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 0.08 h / 0 °C / Inert atmosphere
2: sodium azide; dmap / toluene; N,N-dimethyl-formamide / Inert atmosphere
3: ammonium hydroxide / toluene; N,N-dimethyl-formamide; water / 90 °C / Inert atmosphere
With
dmap; ammonium hydroxide; sodium azide; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
water; N,N-dimethyl-formamide; toluene;
3: |Curtius Rearrangement;
DOI:10.1021/acs.joc.9b01697