(+/-)-melanervin-tetraacetate

Base Information

• Chemical Name: (+/-)-melanervin-tetraacetate
• CAS No.: 60715-60-8
• Molecular Formula: C₃₉H₃₆O₁₁
• Molecular Weight: 680.708
• Mol file: 60715-60-8.mol

Synonyms:

Chemical Property of (+/-)-melanervin-tetraacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-melanervin-tetraacetate

There total 14 articles about (+/-)-melanervin-tetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-benzyloxy-3-methyl-4,6-dimethoxymethyl-benzophenone (74627-91-1) → (+/-)-melanervin-tetraacetate (60715-60-8,82571-10-6)

Guidance literature:

Multi-step reaction with 7 steps

1: 89 percent / 10percent HCl / methanol / 0.67 h / Heating

2: 96 percent / K₂CO₃ / acetone / 0.17 h / Heating

3: 51 percent / K₂CO₃ / dimethylformamide / 0.33 h / Heating

4: 93 percent / LiAlH₄ / diethyl ether / 1 h / Ambient temperature

5: 75 percent / BF₃-etherate / dioxane / 1 h / Ambient temperature

6: 76 percent / H₂ / 10percent Pd-C / methanol / Ambient temperature

7: pyridine / Ambient temperature

With pyridine; hydrogenchloride; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; hydrogen; potassium carbonate; palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; N,N-dimethyl-formamide; acetone;

DOI:10.1016/0040-4020(82)85056-4

Reference yield:

(+/-)-7-Hydroxy-5-methoxy-6-methyl-flavanone (1230-20-2) → (+/-)-melanervin-tetraacetate (60715-60-8,82571-10-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 83 percent / BF₃-etherate / dioxane / 0.5 h / Ambient temperature

2: 29 percent / AlCl₃ / acetonitrile / 0.25 h / Heating

3: 76 percent / H₂ / 10percent Pd-C / methanol / Ambient temperature

4: pyridine / Ambient temperature

With pyridine; aluminium trichloride; boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In 1,4-dioxane; methanol; acetonitrile;

DOI:10.1016/0040-4020(82)85056-4

Reference yield:

2-benzyloxy-3-methyl-4,6-dihydroxy-benzophenone (74627-92-2) → (+/-)-melanervin-tetraacetate (60715-60-8,82571-10-6)

Guidance literature:

Multi-step reaction with 6 steps

1: 96 percent / K₂CO₃ / acetone / 0.17 h / Heating

2: 51 percent / K₂CO₃ / dimethylformamide / 0.33 h / Heating

3: 93 percent / LiAlH₄ / diethyl ether / 1 h / Ambient temperature

4: 75 percent / BF₃-etherate / dioxane / 1 h / Ambient temperature

5: 76 percent / H₂ / 10percent Pd-C / methanol / Ambient temperature

6: pyridine / Ambient temperature

With pyridine; lithium aluminium tetrahydride; boron trifluoride diethyl etherate; hydrogen; potassium carbonate; palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether; N,N-dimethyl-formamide; acetone;

DOI:10.1016/0040-4020(82)85056-4

upstream raw materials:

(+/-)-melanervin

acetic anhydride

3-methyl-2,4,6-trihydroxybenzophenone

2,4-dihydroxy-6-methoxy-5-methyl-acetophenone