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(2S)-1,1-di(3-tolyl)valinol hydrochloride

Base Information
  • Chemical Name:(2S)-1,1-di(3-tolyl)valinol hydrochloride
  • CAS No.:1350923-50-0
  • Molecular Formula:C19H25NO*ClH
  • Molecular Weight:319.875
  • Hs Code.:
(2S)-1,1-di(3-tolyl)valinol hydrochloride

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Chemical Property of (2S)-1,1-di(3-tolyl)valinol hydrochloride
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Technology Process of (2S)-1,1-di(3-tolyl)valinol hydrochloride

There total 1 articles about (2S)-1,1-di(3-tolyl)valinol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; water; In 1,4-dioxane; Inert atmosphere;
DOI:10.1021/jo2019653
Guidance literature:
Multi-step reaction with 2 steps
1: triethylamine / 1,4-dioxane / 2 h / 0 °C / Inert atmosphere
2: methanesulfonic acid / dichloromethane / 0 - 20 °C / Inert atmosphere
With methanesulfonic acid; triethylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jo2019653
Guidance literature:
Multi-step reaction with 3 steps
1: triethylamine / 1,4-dioxane / 2 h / 0 °C / Inert atmosphere
2: methanesulfonic acid / dichloromethane / 0 - 20 °C / Inert atmosphere
3: potassium hydride / toluene / 20 - 120 °C / Inert atmosphere
With methanesulfonic acid; potassium hydride; triethylamine; In 1,4-dioxane; dichloromethane; toluene;
DOI:10.1021/jo2019653
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