Benzenesulfonic acid, 4-methyl-, propylidenehydrazide

Base Information

• Chemical Name: Benzenesulfonic acid, 4-methyl-, propylidenehydrazide
• CAS No.: 103041-47-0
• Molecular Formula: C10H14N2O2S
• Molecular Weight: 226.299
• Mol file: 103041-47-0.mol

Synonyms:

Chemical Property of Benzenesulfonic acid, 4-methyl-, propylidenehydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonic acid, 4-methyl-, propylidenehydrazide

There total 2 articles about Benzenesulfonic acid, 4-methyl-, propylidenehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propionaldehyde (123-38-6) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 4-methyl-N'-propylidenebenzenesulfonohydrazide (103041-47-0)

Guidance literature:

In 1,4-dioxane; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1039/c5ra04050g

Reference yield:

→ 4-methyl-N'-propylidenebenzenesulfonohydrazide (103041-47-0)

Guidance literature:

Touol-4-sufonyl-hydrazin , Eintragen von Propionaldehyd ;

DOI:10.1021/ja01082a058

Reference yield: 71.0%

2-phenyl-2,3-dihydro-4(1H)-quinazolinone (121998-76-3,954-91-6) + 4-methyl-N'-propylidenebenzenesulfonohydrazide (103041-47-0) → 2-phenyl-3-n-propylquinazoline-4(3H)-one (26060-02-6)

Guidance literature:

With rhodium(II) acetate dimer; potassium carbonate; In 1,4-dioxane; at 90 ℃; for 4h;

DOI:10.1002/adsc.201500678

upstream raw materials:

propionaldehyde

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

5-[(1-propyl)sulfanyl]-1-phenyl-1H-tetrazole

2-phenyl-3-n-propylquinazoline-4(3H)-one

N-(n-propyl)benzamide

3-Ethyl-6-methyl-s-triazolo<4,3-a>pyridin

Refernces

• 1、 Inturi, Surendra Babu,Kalita, Biswajit,Ahamed, A. Jafar. "I2-TBHP-catalyzed one-pot highly efficient synthesis of 4,3-fused 1,2,4-triazoles from: N -tosylhydrazones and aromatic N-heterocycles via intermolecular formal 1,3-dipolar cycloaddition". supporting information. p. 11061 - 11064. Retrieved 2016/12/07.
• 2、 Li, Le-Le,Gao, Lian-Xun,Han, Fu-She. "A straightforward synthesis of alkyl 1H-tetrazol-5-yl thioethers via a one-pot reaction of aldehydes and 1H-tetrazole-5-thiols mediated by N-tosylhydrazones". . p. 29996 - 30000. Retrieved 2015/05/13.