2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate

Base Information

• Chemical Name: 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate
• CAS No.: 78328-83-3
• Molecular Formula: C₁₇H₁₈FNO₈S₂
• Molecular Weight: 447.462
• Mol file: 78328-83-3.mol

Synonyms:

Chemical Property of 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate

There total 2 articles about 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.1%

2-nitro-2-fluoropropane-1,3-diol (4776-99-2) + p-toluenesulfonyl chloride (98-59-9) → 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate (78328-83-3)

Guidance literature:

With pyridine; for 17h;

DOI:10.1021/jo00332a011

Reference yield: 10.0%

2-nitro-2-fluoropropane-1,3-diol (4776-99-2) + p-toluenesulfonyl chloride (98-59-9) → 2-fluoro-3-hydroxy-2-nitro-1-propyl p-toluenesulfonate (78328-82-2) + 2-fluoro-2-nitro-1,3-propylene di-p-toluenesulfonate (78328-83-3)

Guidance literature:

With pyridine; In chloroform; for 5h; Heating;

DOI:10.1021/jo00332a011

upstream raw materials:

2-nitro-2-fluoropropane-1,3-diol

p-toluenesulfonyl chloride