C₁₁H₁₂BrNO₂

Base Information

• Chemical Name: C₁₁H₁₂BrNO₂
• CAS No.: 1452161-82-8
• Molecular Formula: C₁₁H₁₂BrNO₂
• Molecular Weight: 270.126
• Mol file: 1452161-82-8.mol

Synonyms:

Chemical Property of C₁₁H₁₂BrNO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₂BrNO₂

There total 4 articles about C₁₁H₁₂BrNO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-(2-methoxycarbonylaminophenyl)-2-propenol (1452161-71-5) → C11H12BrNO2 (1452161-82-8)

Guidance literature:

With phosphorus tribromide; In diethyl ether; at 20 ℃; for 0.5h; Cooling with ice;

DOI:10.1039/c3cc43257b

Reference yield:

2-nitrocinnamaldehyde (1466-88-2,66894-06-2) → C11H12BrNO2 (1452161-82-8)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium tetrahydroborate / methanol / 0.5 h / 20 °C / Cooling with ice

2: ammonium hydroxide; iron(II) sulfate heptahydrate / methanol; water / 4 h / 80 °C

3: sodium hydrogencarbonate / acetone / 2 h / Cooling with ice

4: phosphorus tribromide / diethyl ether / 0.5 h / 20 °C / Cooling with ice

With ammonium hydroxide; sodium tetrahydroborate; iron(II) sulfate heptahydrate; phosphorus tribromide; sodium hydrogencarbonate; In methanol; diethyl ether; water; acetone;

DOI:10.1039/c3cc43257b

Reference yield:

3-(2-nitrophenyl)prop-2-en-1-ol (1504-65-0) → C11H12BrNO2 (1452161-82-8)

Guidance literature:

Multi-step reaction with 3 steps

1: ammonium hydroxide; iron(II) sulfate heptahydrate / methanol; water / 4 h / 80 °C

2: sodium hydrogencarbonate / acetone / 2 h / Cooling with ice

3: phosphorus tribromide / diethyl ether / 0.5 h / 20 °C / Cooling with ice

With ammonium hydroxide; iron(II) sulfate heptahydrate; phosphorus tribromide; sodium hydrogencarbonate; In methanol; diethyl ether; water; acetone;

DOI:10.1039/c3cc43257b

upstream raw materials:

3-(2-nitrophenyl)prop-2-en-1-ol

2-nitrocinnamaldehyde

3-(2-aminophenyl)prop-2-en-1-ol

(E)-3-(2-methoxycarbonylaminophenyl)-2-propenol

Downstream raw materials:

(E)-N-methoxycarbonyl-3-(2-methoxycarbonylaminophenyl)-2-propeneamine

C₁₁H₁₂N₄O₂

C₁₁H₁₄N₂O₂