5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one

Base Information

• Chemical Name: 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one
• CAS No.: 80256-74-2
• Molecular Formula: C₂₆H₃₄O
• Molecular Weight: 362.555
• Mol file: 80256-74-2.mol

Synonyms:

Chemical Property of 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one

There total 8 articles about 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nonanone-5 (502-56-7) → 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one (80256-74-2)

Guidance literature:

Multi-step reaction with 8 steps

1: 67.3 g / Zn / benzene / 1.5 h / Heating

2: 1.) formic acide, 2.) H₂ / 2.) 5 percent Pd/C / 1.) 1 h, reflux; 2.) methanol, rt

3: 35.5 g / LiAlH₄ / diethyl ether / 2 h / Heating

4: 33.4 g / PBr₃ / 1.) 0 deg C up to rt., 2.) 60 deg C, 1.5 h

5: sodium ethylate / ethanol / 4 h / Heating

6: 5.8 g / aq. sodium carbonate / methanol / 2 h / Heating

7: thionyl chloride / 1 h / Heating

8: AlCl₃ / CS₂ / 2 h / Heating

With lithium aluminium tetrahydride; aluminium trichloride; formic acid; thionyl chloride; hydrogen; sodium ethanolate; phosphorus tribromide; sodium carbonate; zinc; palladium on activated charcoal; In methanol; carbon disulfide; diethyl ether; ethanol; benzene;

DOI:10.1016/S0040-4020(01)92352-X

Reference yield:

butyl-3 hydroxy-3 heptanoate d'ethyle (80256-55-9) → 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one (80256-74-2)

Guidance literature:

Multi-step reaction with 7 steps

1: 1.) formic acide, 2.) H₂ / 2.) 5 percent Pd/C / 1.) 1 h, reflux; 2.) methanol, rt

2: 35.5 g / LiAlH₄ / diethyl ether / 2 h / Heating

3: 33.4 g / PBr₃ / 1.) 0 deg C up to rt., 2.) 60 deg C, 1.5 h

4: sodium ethylate / ethanol / 4 h / Heating

5: 5.8 g / aq. sodium carbonate / methanol / 2 h / Heating

6: thionyl chloride / 1 h / Heating

7: AlCl₃ / CS₂ / 2 h / Heating

With lithium aluminium tetrahydride; aluminium trichloride; formic acid; thionyl chloride; hydrogen; sodium ethanolate; phosphorus tribromide; sodium carbonate; palladium on activated charcoal; In methanol; carbon disulfide; diethyl ether; ethanol;

DOI:10.1016/S0040-4020(01)92352-X

Reference yield:

3-butylheptan-1-ol (51655-56-2) → 5-Butyl-1-(9H-fluoren-2-yl)-nonan-1-one (80256-74-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 33.4 g / PBr₃ / 1.) 0 deg C up to rt., 2.) 60 deg C, 1.5 h

2: sodium ethylate / ethanol / 4 h / Heating

3: 5.8 g / aq. sodium carbonate / methanol / 2 h / Heating

4: thionyl chloride / 1 h / Heating

5: AlCl₃ / CS₂ / 2 h / Heating

With aluminium trichloride; thionyl chloride; sodium ethanolate; phosphorus tribromide; sodium carbonate; In methanol; carbon disulfide; ethanol;

DOI:10.1016/S0040-4020(01)92352-X

upstream raw materials:

9H-fluorene

chlorure de l'acide butyl-5 nonanique

nonanone-5

3-butylheptan-1-ol

Downstream raw materials:

2-(5-Butyl-nonyl)-9H-fluorene