1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole

Base Information

Chemical Name:1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole
CAS No.:20409-91-0
Molecular Formula:C22H20 N2 O2 S
Molecular Weight:376.479
Hs Code.:
NSC Number:137966
DSSTox Substance ID:DTXSID60300639
Nikkaji Number:J2.776.764H

Synonyms:20409-91-0;1-[(4-methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole;NSC137966;DTXSID60300639;NSC-137966

Suppliers and Price of 1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole

Chemical Property:

Vapor Pressure:5.82E-12mmHg at 25°C
Boiling Point:545.6°C at 760 mmHg
Flash Point:283.8°C
Density:1.22g/cm³
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:376.12454906
Heavy Atom Count:27
Complexity:619

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole

There total 6 articles about 1-[(4-Methylphenyl)sulfonyl]-3,5-diphenyl-4,5-dihydro-1h-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 156605-56-0
1-phenylethan-1-one O-pivaloyl oxime

: 51608-60-7
N-(benzylidene)-p-methylbenzenesulfonamide

: 20409-91-0
3,5-diphenyl-1-tosyl-4,5-dihydro-1H-pyrazole

Guidance literature:: With copper diacetate; copper(l) chloride; In dimethyl sulfoxide; at 100 ℃; for 8h;
DOI:10.1021/ol500094w

Reference yield: 79.0%

: 94-41-7
benzalacetophenone

: 1576-35-8
toluene-4-sulfonic acid hydrazide

: 20409-91-0
3,5-diphenyl-1-tosyl-4,5-dihydro-1H-pyrazole

Guidance literature:: With acetic acid; In ethylene glycol; for 0.416667h; Solvent; Time; Microwave irradiation; Green chemistry;
DOI:10.1002/jccs.201500385

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 20409-91-0
3,5-diphenyl-1-tosyl-4,5-dihydro-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / benzene / 2 h / 60 - 70 °C

2: acetic acid / ethylene glycol / 0.42 h / Microwave irradiation; Green chemistry

With hydrazine hydrate; acetic acid; In ethylene glycol; benzene;
DOI:10.1002/jccs.201500385