2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid

Base Information

• Chemical Name: 2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid
• CAS No.: 10328-28-6
• Molecular Formula: C18H20N2O6
• Molecular Weight: 360.367
• ChEMBL ID: CHEMBL21547
• DSSTox Substance ID: DTXSID90467082
• Nikkaji Number: J1.158.444F
• Wikidata: Q82293864
• Mol file: 10328-28-6.mol

Synonyms:10328-28-6;2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid;CHEMBL21547;SCHEMBL394404;DTXSID90467082;ethylenebis-(2-hydroxyphenylglycine);2-[N-[2-[N-(carboxymethyl)-2-hydroxyanilino]ethyl]-2-hydroxyanilino]acetic acid;FT-0776027;2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diaceticacid;2,2'-{Ethane-1,2-diylbis[(2-hydroxyphenyl)azanediyl]}diacetic acid (non-preferred name)

Chemical Property of 2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid

Chemical Property:

• XLogP3: 2.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 9
• Exact Mass: 360.13213636
• Heavy Atom Count: 26
• Complexity: 433

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N(CCN(CC(=O)O)C2=CC=CC=C2O)CC(=O)O)O

Technology Process of 2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid

There total 1 articles about 2,2'-(Ethane-1,2-diylbis((2-hydroxyphenyl)azanediyl))diacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(2-methoxyphenyl)ethylenediamine (37460-52-9) + bromoacetic acid methyl ester (96-32-2) → N,N'-bis(2-methoxyphenyl)ethylenediamine-N,N'-diacetic acid (10328-28-6)

Guidance literature:

With calcium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2h;

DOI:10.1021/jm00157a020

Reference yield:

N,N'-bis(2-hydroxyphenyl)ethylenediamine-N,N'-diacetic acid (10328-28-6) + copper(II) nitrate → {Cu((C6H4OH)N(CH2COO)CH2)2} (131397-04-1,21989-48-0)

Guidance literature:

In water; glycerol; from Cu(NO3)2 and HPED below pH 5.5 in glycerol-water, freezing to 77 K; not isolated, detn. by ESR;

DOI:10.1016/S0277-5387(00)86578-X

Reference yield:

N,N'-bis(2-hydroxyphenyl)ethylenediamine-N,N'-diacetic acid (10328-28-6) + copper(II) nitrate → {Cu(C6H4O)(N(CH2COO)CH2)2(C6H4OH)}(1-) + {Cu((C6H4OH)N(CH2COO)CH2)2} (131397-04-1,21989-48-0)

Guidance literature:

In water; glycerol; from Cu(NO3)2 and HPED at pH 6.26 in glycerol-water, freezing to 77 K; not isolated, detn. by ESR;

DOI:10.1016/S0277-5387(00)86578-X

upstream raw materials:

N,N'-bis(2-methoxyphenyl)ethylenediamine

bromoacetic acid methyl ester

Downstream raw materials:

{Cu((C₆H₄OH)N(CH₂COO)CH₂)2}