Technology Process of 2-[1-(6-Oxo-cyclohex-1-enyl)-ethyl]-malonic acid dimethyl ester
There total 6 articles about 2-[1-(6-Oxo-cyclohex-1-enyl)-ethyl]-malonic acid dimethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: MCPBA / CH2Cl2
2: H2NCH2CH2NMe2 / dimethylformamide / 48 h / 80 °C
3: pyridinium chlorochromate / CH2Cl2 / 2 h
4: 1) NaH / 1) DMF, 2) DMF, rt, 1.5 h
With
sodium hydride; N,N-dimethylethylenediamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)89067-0
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2NCH2CH2NMe2 / benzene
2: MCPBA / CH2Cl2
3: H2NCH2CH2NMe2 / dimethylformamide / 48 h / 80 °C
4: pyridinium chlorochromate / CH2Cl2 / 2 h
5: 1) NaH / 1) DMF, 2) DMF, rt, 1.5 h
With
sodium hydride; N,N-dimethylethylenediamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate;
In
dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1016/S0040-4020(01)89067-0
- Guidance literature:
-
Multi-step reaction with 3 steps
1: H2NCH2CH2NMe2 / dimethylformamide / 48 h / 80 °C
2: pyridinium chlorochromate / CH2Cl2 / 2 h
3: 1) NaH / 1) DMF, 2) DMF, rt, 1.5 h
With
sodium hydride; N,N-dimethylethylenediamine; pyridinium chlorochromate;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)89067-0
