(3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid

Base Information

• Chemical Name: (3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid
• CAS No.: 1206832-66-7
• Molecular Formula: C₂₉H₄₆N₂O₆
• Molecular Weight: 518.694
• Mol file: 1206832-66-7.mol

Synonyms:

Chemical Property of (3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid

There total 1 articles about (3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

(R)-tert-butyl-5-{(R)-3-(tert-butoxycarbonyl)-2-[N-benzyl-N-((2-methoxy-7,7-dimethylbicyclo[2,2,1]heptan-1-yl)methyl)amino]-propyl}-2,2-dimethyloxazolidine-3-carboxylate (1037825-12-9) + di-tert-butyl dicarbonate (24424-99-5) → C29H44N2O5 (1206832-68-9) + (3R)-3-(benzyl((2-methoxy-7,7-dimethylbicyclo[2.2.1]heptan-1-yl)methyl)amino)-6-(tert-butoxycarbonyl amino)-5-hydroxyhexanoic acid (1206832-66-7)

Guidance literature:

(R)-tert-butyl-5-{(R)-3-(tert-butoxycarbonyl)-2-[N-benzyl-N-((2-methoxy-7,7-dimethylbicyclo[2,2,1]heptan-1-yl)methyl)amino]-propyl}-2,2-dimethyloxazolidine-3-carboxylate; With hydrogenchloride; In 1,4-dioxane; water; at 60 ℃; for 1.5h;

di-tert-butyl dicarbonate; With triethylamine; In tetrahydrofuran; at 20 ℃; for 3.5h;

DOI:10.1016/j.tet.2009.10.097

upstream raw materials:

(R)-tert-butyl-5-{(R)-3-(tert-butoxycarbonyl)-2-[N-benzyl-N-((2-methoxy-7,7-dimethylbicyclo[2,2,1]heptan-1-yl)methyl)amino]-propyl}-2,2-dimethyloxazolidine-3-carboxylate

di-tert-butyl dicarbonate