(R*,R*)-2--5-pentanolide

Base Information

• Chemical Name: (R*,R*)-2--5-pentanolide
• CAS No.: 139367-47-8
• Molecular Formula: C₁₅H₂₂O₃Si
• Molecular Weight: 278.423
• Mol file: 139367-47-8.mol

Synonyms:

Chemical Property of (R*,R*)-2--5-pentanolide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R*,R*)-2--5-pentanolide

There total 4 articles about (R*,R*)-2--5-pentanolide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

((3,4-dihydro-2H-pyran-6-yl)oxy)trimethylsilane (71309-70-1) + 2-trimethylsilylbenzaldehyde (17887-55-7) → (R*,S*)-2--5-pentanolide (139367-47-8,139390-82-2) + (R*,R*)-2--5-pentanolide (139367-47-8,139390-82-2)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1248/cpb.39.2863

Reference yield:

((3,4-dihydro-2H-pyran-6-yl)oxy)trimethylsilane (71309-70-1) + 2-trimethylsilylbenzaldehyde (17887-55-7) → (R*,S*)-2--5-pentanolide (139367-47-8,139390-82-2) + (R*,R*)-2--5-pentanolide (139367-47-8,139390-82-2)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -78 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1248/cpb.39.2863

Reference yield:

((3,4-dihydro-2H-pyran-6-yl)oxy)trimethylsilane (71309-70-1) → (R*,S*)-2--5-pentanolide (139367-47-8,139390-82-2) + (R*,R*)-2--5-pentanolide (139367-47-8,139390-82-2)

Guidance literature:

With ammonium cerium(IV) nitrate; boron trifluoride diethyl etherate; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) CH₂Cl₂, -78 deg C, 2.) MeOH, -20 deg C, 20 min;

DOI:10.1248/cpb.39.2863

upstream raw materials:

((3,4-dihydro-2H-pyran-6-yl)oxy)trimethylsilane

2-trimethylsilylbenzaldehyde