N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin

Base Information

• Chemical Name: N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin
• CAS No.: 100324-99-0
• Molecular Formula: C₄₇H₅₂N₂O₂₁
• Molecular Weight: 980.931
• Mol file: 100324-99-0.mol

Synonyms:

Chemical Property of N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin

There total 4 articles about N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin-tert-butylester (100324-98-9) → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin (100324-99-0)

Guidance literature:

With formic acid; for 16h; Ambient temperature;

Reference yield:

2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide (87376-57-6) → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin (100324-99-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 67 percent / AgClO₄, molecular sieve / CH₂Cl₂; toluene / -50 °C

2: 1.) H₂S, (C₂H₅)3N / 1.) pyridine, water, 18 h, room temperature, 2.) 20 h, room temperature

3: 99 percent / 98 percent HCOOH / 16 h / Ambient temperature

With formic acid; molecular sieve; hydrogen sulfide; silver perchlorate; triethylamine; In dichloromethane; toluene;

Reference yield:

2-benzyloxycarbonylamino-3-hydroxy-propionic acid tert-butyl ester (59859-77-7) → N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin (100324-99-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 67 percent / AgClO₄, molecular sieve / CH₂Cl₂; toluene / -50 °C

2: 1.) H₂S, (C₂H₅)3N / 1.) pyridine, water, 18 h, room temperature, 2.) 20 h, room temperature

3: 99 percent / 98 percent HCOOH / 16 h / Ambient temperature

With formic acid; molecular sieve; hydrogen sulfide; silver perchlorate; triethylamine; In dichloromethane; toluene;

upstream raw materials:

N-(Benzyloxycarbonyl)-O-<(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-O-(2-acetamido-4,6-di-O-benzoyl-2-desoxy-α-D-galactopyranosyl)>-L-serin-tert-butylester

2-azido-4,6-di-O-benzoyl-2-deoxy-3-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-α-D-galactopyranosyl bromide

2-benzyloxycarbonylamino-3-hydroxy-propionic acid tert-butyl ester

Refernces