2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide

Base Information

Chemical Name:2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide
CAS No.:215362-24-6
Molecular Formula:C₁₇H₁₅NO₂
Molecular Weight:265.312
Hs Code.:
DSSTox Substance ID:DTXSID501192649

Synonyms:DTXSID501192649;2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide;215362-24-6

Suppliers and Price of 2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:265.110278721
Heavy Atom Count:20
Complexity:373

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(=O)C2=C1C=CC=C2C(=O)NCC3=CC=CC=C3

Technology Process of 2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide

There total 1 articles about 2,3-Dihydro-3-oxo-N-(phenylmethyl)-1H-indene-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71005-12-4
3-oxo-indan-4-carboxylic acid

: 100-46-9
benzylamine

: 215362-24-6
7-N-benzylcarbamoyl-1-indanone

Guidance literature:: With ammonia; 1,1'-carbonyldiimidazole; Yield given. Multistep reaction; 1) CH₂Cl₂, r.t., 2 h, 2) CH₂Cl₂, r.t., 14 h;
DOI:10.1002/(SICI)1521-4184(199802)331:2<59::AID-ARDP59>3.3.CO;2-4

Reference yield:

: 215362-24-6
7-N-benzylcarbamoyl-1-indanone

: 215362-55-3
(S)-(+)-7-N-benzylcarbamoyl-1-aminoindan

Guidance literature:: Multi-step reaction with 3 steps

1: TsOH / toluene / Heating

2: 60 percent / H₂ / Raney Nickel / ethanol / 3750.3 Torr / Ambient temperature

3: 73 percent / ammonium formate / 10percent Pd/C / methanol / 1 h / Heating

With hydrogen; ammonium formate; toluene-4-sulfonic acid; palladium on activated charcoal; nickel; In methanol; ethanol; toluene;
DOI:10.1002/(SICI)1521-4184(199802)331:2<59::AID-ARDP59>3.3.CO;2-4

Reference yield:

: 215362-24-6
7-N-benzylcarbamoyl-1-indanone

: (S)-3-Dipropylamino-indan-4-carboxylic acid cyclohexylmethyl-amide

Guidance literature:: Multi-step reaction with 4 steps

1: TsOH / toluene / Heating

2: 60 percent / H₂ / Raney Nickel / ethanol / 3750.3 Torr / Ambient temperature

3: 68 percent / H₂ / 10percent Pd/C / ethanol / 60 h / 60 °C / 3750.3 Torr

4: 45 percent / NaBH₄ / toluene / Heating

With sodium tetrahydroborate; hydrogen; toluene-4-sulfonic acid; palladium on activated charcoal; nickel; In ethanol; toluene;
DOI:10.1002/(SICI)1521-4184(199802)331:2<59::AID-ARDP59>3.3.CO;2-4