5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole

Base Information

Chemical Name:5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole
CAS No.:103499-22-5
Molecular Formula:C₁₅H₁₁N₃O
Molecular Weight:249.272
Hs Code.:
DSSTox Substance ID:DTXSID301327670
ChEMBL ID:CHEMBL1713227
Mol file:103499-22-5.mol

Synonyms:MLS000706744;5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole;SMR000288196;4-[5-((E)-Styryl)-[1,2,4]oxadiazol-3-yl]-pyridine;CHEMBL1713227;BDBM93831;cid_5740237;4-{5-[(E)-2-phenylethenyl]-1,2,4-oxadiazol-3-yl}pyridine;DTXSID301327670;HMS2723I07;HMS3449K06;STK323391;AKOS000645802;CCG-146699;103499-22-5;3-(4-pyridyl)-5-[(E)-styryl]-1,2,4-oxadiazole

Suppliers and Price of 5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:249.090211983
Heavy Atom Count:19
Complexity:296

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=CC2=NC(=NO2)C3=CC=NC=C3
Isomeric SMILES:C1=CC=C(C=C1)/C=C/C2=NC(=NO2)C3=CC=NC=C3

Technology Process of 5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole

There total 3 articles about 5-[(E)-2-phenylethenyl]-3-pyridin-4-yl-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-48-1
pyridine-4-carbonitrile

: 103499-22-5
3-(4-pyridyl)-5-styryl-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 53 percent / hydroxylamine hydrochloride, aq. NaOH / aq. ethanol / Heating

2: K₂CO₃ / acetone / 2 h / Ambient temperature

3: 2 h / 150 °C

With sodium hydroxide; hydroxylamine hydrochloride; potassium carbonate; In ethanol; acetone;
DOI:10.1021/jm00161a008

Reference yield:

: 1594-57-6,849833-58-5
pyridine-4-carboxamidoxime

: 103499-22-5
3-(4-pyridyl)-5-styryl-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / acetone / 2 h / Ambient temperature

2: 2 h / 150 °C

With potassium carbonate; In acetone;
DOI:10.1021/jm00161a008