Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester

Base Information

• Chemical Name: Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester
• CAS No.: 164322-56-9
• Molecular Formula: C₂₂H₂₃F₃O₈S
• Molecular Weight: 504.481
• Mol file: 164322-56-9.mol

Synonyms:

Chemical Property of Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester

There total 1 articles about Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + methyl 4,6-O-benzylidene-α-D-galactopyranoside 2-O-benzoate (116002-34-7) → Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester (164322-56-9)

Guidance literature:

With pyridine; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1021/jo00119a011

Reference yield:

Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester (164322-56-9) → (2R,3R,4E)-1,3-O-Benzylidene-5-(benzyloxy)-2-O-formyl-4-pentene-1,2,3-triol

Guidance literature:

With pyridine; 1,1,1,3',3',3'-hexafluoro-propanol; water; In dichloromethane; for 1h; Yield given; Heating;

DOI:10.1021/jo00119a011

Reference yield:

Trifluoro-methanesulfonic acid (2S,4aR,6S,7R,8S,8aS)-7-benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester (164322-56-9) → Benzyl 3,5-O-benzylidene-2-deoxy-α-D-threo-pentofuranoside + (2R,3R,4E)-1,3-O-Benzylidene-5-(benzyloxy)-2-O-formyl-4-pentene-1,2,3-triol

Guidance literature:

With pyridine; 1,1,1,3',3',3'-hexafluoro-propanol; water; In dichloromethane; for 1h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/jo00119a011

upstream raw materials:

trifluoromethylsulfonic anhydride

methyl 4,6-O-benzylidene-α-D-galactopyranoside 2-O-benzoate