Chemical Property of Tesetaxel
Chemical Property:
- Melting Point:147-149 °C
- Boiling Point:880.5±65.0 °C(Predicted)
- PKA:10.17±0.46(Predicted)
- PSA：201.51000
- Density:1.34±0.1 g/cm3(Predicted)
- LogP:4.95550
- XLogP3:3.3
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:16
- Rotatable Bond Count:15
- Exact Mass:881.41101714
- Heavy Atom Count:63
- Complexity:1780
- Purity/Quality:
-
98% *data from raw suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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Useful:
- Canonical SMILES:CC1=C2C3C(C4(CCC5C(C4C(C(C2(C)C)(CC1OC(=O)C(C(C6=C(C=CC=N6)F)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=O)C)C)OC(O3)CN(C)C
- Isomeric SMILES:CC1=C2[C@@H]3[C@H]([C@@]4(CC[C@@H]5[C@]([C@H]4[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C6=C(C=CC=N6)F)NC(=O)OC(C)(C)C)O)O)OC(=O)C7=CC=CC=C7)(CO5)OC(=O)C)C)O[C@@H](O3)CN(C)C
- Recent ClinicalTrials:Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC
- Recent EU Clinical Trials:A Multicenter, Phase 2 Study of Tesetaxel plus Three Different PD-(L)1 Inhibitors in Patients with Triple-Negative, Locally Advanced or Metastatic Breast Cancer and Tesetaxel Monotherapy in Elderly Patients with HER2 Negative, Locally Advanced or Metastatic Breast Cancer
