C₄₂H₄₆F₂N₄O₂

Base Information

• Chemical Name: C₄₂H₄₆F₂N₄O₂
• CAS No.: 1443258-07-8
• Molecular Formula: C₄₂H₄₆F₂N₄O₂
• Molecular Weight: 676.85
• Mol file: 1443258-07-8.mol

Synonyms:

Chemical Property of C₄₂H₄₆F₂N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₆F₂N₄O₂

There total 3 articles about C₄₂H₄₆F₂N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5,15-(4-fluorophenyl)-5,15-(ethylpropionate)-10,10,20,20-tetramethylcalix[4]pyrrole (1443258-06-7) → C42H46F2N4O2 (1443258-07-8)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; for 24.6667h; Inert atmosphere; Reflux;

DOI:10.1002/chem.201300472

Reference yield:

ethyl 4-(4-fluorophenyl)-4-oxobutanoate (41310-80-9) → C42H46F2N4O2 (1443258-07-8)

Guidance literature:

Multi-step reaction with 3 steps

1: trifluoroacetic acid / 72 h / Inert atmosphere; Reflux

2: boron trifluoride diethyl etherate / 12 h / 20 °C

3: sodium tetrahydroborate / tetrahydrofuran; methanol / 24.67 h / Inert atmosphere; Reflux

With sodium tetrahydroborate; boron trifluoride diethyl etherate; trifluoroacetic acid; In tetrahydrofuran; methanol;

DOI:10.1002/chem.201300472

Reference yield:

5-(4-fluorophenyl)-5-(ethyl propionate)dipyrromethane (1443258-05-6) → C42H46F2N4O2 (1443258-07-8)

Guidance literature:

Multi-step reaction with 2 steps

1: boron trifluoride diethyl etherate / 12 h / 20 °C

2: sodium tetrahydroborate / tetrahydrofuran; methanol / 24.67 h / Inert atmosphere; Reflux

With sodium tetrahydroborate; boron trifluoride diethyl etherate; In tetrahydrofuran; methanol;

DOI:10.1002/chem.201300472

upstream raw materials:

ethyl 4-(4-fluorophenyl)-4-oxobutanoate

5,15-(4-fluorophenyl)-5,15-(ethylpropionate)-10,10,20,20-tetramethylcalix[4]pyrrole

5-(4-fluorophenyl)-5-(ethyl propionate)dipyrromethane