2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol

Base Information

• Chemical Name: 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol
• CAS No.: 76583-98-7
• Molecular Formula: C₁₅H₁₇NOS
• Molecular Weight: 263.34
• Mol file: 76583-98-7.mol

Synonyms:

Chemical Property of 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol

There total 8 articles about 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-carbethoxy-2'-<(methylamino)carbonyl>diphenyl sulfide (62220-56-8) → 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol (76583-98-7)

Guidance literature:

With lithium aluminium deuteride; In tetrahydrofuran; Ambient temperature;

DOI:10.1021/jo00321a020

Reference yield:

2-carbethoxy-2'-chlorocarbonyldiphenyl sulfide (62220-53-5) → 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol (76583-98-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / dioxane; H₂O / 1 h

2: LiAlD₄ / tetrahydrofuran / Ambient temperature

With lithium aluminium deuteride; In tetrahydrofuran; 1,4-dioxane; water;

DOI:10.1021/jo00321a020

Reference yield:

2,2'-thiodibenzoic acid (22219-02-9) → 2-<<2-<(methylamino)methyl-d2>phenyl>thio>benzyl-α-α-d2 alcohol (76583-98-7)

Guidance literature:

Multi-step reaction with 6 steps

1: thionyl chloride / 5 h / 60 °C

2: 0.5 h / Heating

3: 37 percent / KOH / ethanol / 96 h / Ambient temperature

4: 20.1 g / thionyl chloride

5: 96 percent / dioxane; H₂O / 1 h

6: LiAlD₄ / tetrahydrofuran / Ambient temperature

With potassium hydroxide; thionyl chloride; lithium aluminium deuteride; In tetrahydrofuran; 1,4-dioxane; ethanol; water;

DOI:10.1021/jo00321a020

upstream raw materials:

2-carbethoxy-2'-<(methylamino)carbonyl>diphenyl sulfide

2-carbethoxy-2'-chlorocarbonyldiphenyl sulfide

2,2'-thiodibenzoic acid

2-carbethoxy-2'-carboxydiphenyl sulfide

Downstream raw materials:

6-benzyl-6,7-dihydro-6-methyl-5H-dibenzo<1,5>thiazocinium-5,5,7,7-d4 bromide