o-azidocinnamylamine

Base Information

• Chemical Name: o-azidocinnamylamine
• CAS No.: 153896-08-3
• Molecular Formula: C₉H₁₀N₄
• Molecular Weight: 174.205
• Mol file: 153896-08-3.mol

Synonyms:

Chemical Property of o-azidocinnamylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of o-azidocinnamylamine

There total 3 articles about o-azidocinnamylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrocinnamaldehyde (1466-88-2,66894-06-2) → o-azidocinnamylamine (153896-08-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium borohydride / 2.) Pd

2: 1.) diazotation, 2.) azidation

3: 1.) N-chlorosuccinimide, dimethylsulfide, 2.) potassium phthalimide / 3.) hydrazinolysis

With sodium tetrahydroborate; N-chloro-succinimide; dimethylsulfide; potassium phtalimide; palladium;

DOI:10.1016/S0040-4039(00)60701-3

Reference yield:

(E)-3-(2-Azido-phenyl)-prop-2-en-1-ol (153896-11-8) → o-azidocinnamylamine (153896-08-3)

Guidance literature:

With N-chloro-succinimide; dimethylsulfide; potassium phtalimide; Yield given. Multistep reaction; 3.) hydrazinolysis;

DOI:10.1016/S0040-4039(00)60701-3

Reference yield:

3-(2-aminophenyl)prop-2-en-1-ol (153896-10-7) → o-azidocinnamylamine (153896-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) diazotation, 2.) azidation

2: 1.) N-chlorosuccinimide, dimethylsulfide, 2.) potassium phthalimide / 3.) hydrazinolysis

With N-chloro-succinimide; dimethylsulfide; potassium phtalimide;

DOI:10.1016/S0040-4039(00)60701-3

upstream raw materials:

(E)-3-(2-Azido-phenyl)-prop-2-en-1-ol

3-(2-aminophenyl)prop-2-en-1-ol

2-nitrocinnamaldehyde

Downstream raw materials:

C₅₄H₄₇N₃P₂

C₅₉H₅₅N₃O₂P₂