[3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium

Base Information

Chemical Name:[3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium
CAS No.:103680-51-9
Molecular Formula:C₉H₁₃ClNO₂P
Molecular Weight:233.634
Hs Code.:
ChEMBL ID:CHEMBL114020
DSSTox Substance ID:DTXSID60559382
Mol file:103680-51-9.mol

Synonyms:103680-51-9;CHEMBL114020;[3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium;DTXSID60559382

Suppliers and Price of [3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:232.0294183
Heavy Atom Count:14
Complexity:195

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CCN)[P+](=O)O)Cl

Technology Process of [3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium

There total 4 articles about [3-Amino-1-(4-chlorophenyl)propyl](hydroxy)oxophosphanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123715-56-0
ethyl 1-(p-chlorophenyl)-2-cyano-ethyl(diethoxymethyl)-phosphinate

: 103680-51-9
3-amino-1-(4-chlorophenyl)propylphosphonous acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, NH₃ / Ni / ethanol

2: HCl, propylene oxide / Heating

With hydrogenchloride; ammonia; hydrogen; methyloxirane; nickel; In ethanol;

Reference yield:

: 28446-72-2,37627-41-1,14378-04-2
(2E)-3-(4-chlorophenyl)acrylonitrile

: 103680-51-9
3-amino-1-(4-chlorophenyl)propylphosphonous acid

Guidance literature:: Multi-step reaction with 3 steps

1: 51 percent / NaOEt / ethanol / 4 h / Ambient temperature

2: 93 percent / NH₃, H₂ / Raney Nickel / ethanol / 750.06 Torr

3: 1.) 36percent aq. HCl 2.) propylene oxide / 1.) reflux 2.) EtOH

With hydrogenchloride; ammonia; hydrogen; sodium ethanolate; methyloxirane; nickel; In ethanol;
DOI:10.1016/S0040-4020(01)89240-1

Reference yield:

: 28446-72-2
4-chlorocinnamonitrile

: 103680-51-9
3-amino-1-(4-chlorophenyl)propylphosphonous acid

Guidance literature:: Multi-step reaction with 3 steps

1: NaOEt / ethanol

2: H₂, NH₃ / Ni / ethanol

3: HCl, propylene oxide / Heating

With hydrogenchloride; ammonia; hydrogen; sodium ethanolate; methyloxirane; nickel; In ethanol;