3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone

Base Information

• Chemical Name: 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone
• CAS No.: 215957-73-6
• Molecular Formula: C₁₉H₃₀N₂O₂S
• Molecular Weight: 350.525
• Mol file: 215957-73-6.mol

Synonyms:

Chemical Property of 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone

There total 4 articles about 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

toluene-4-sulfonic acid hydrazide (1576-35-8) + 3,3-Dibutylcyclobutanone (215957-67-8) → 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone (215957-73-6)

Guidance literature:

In tetrahydrofuran;

Reference yield:

2-(1-butyl)-1-hexene (6795-79-5) → 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone (215957-73-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 66 percent / zinc dust / diethyl ether / 1 h / sonication

2: 90 percent / zinc dust / acetic acid / 0.83 h / 70 °C

3: 54 percent / tetrahydrofuran

With zinc; In tetrahydrofuran; diethyl ether; acetic acid; 1: Cycloaddition / 2: Dehalogenation / 3: Condensation;

Reference yield:

nonanone-5 (502-56-7) → 3,3-Dibutylcyclobutanone toluene-p-sulfonylhydrazone (215957-73-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 58 percent / Sodium hydride / dimethylsulfoxide / 2 h / 50 °C

2: 66 percent / zinc dust / diethyl ether / 1 h / sonication

3: 90 percent / zinc dust / acetic acid / 0.83 h / 70 °C

4: 54 percent / tetrahydrofuran

With sodium hydride; zinc; In tetrahydrofuran; diethyl ether; acetic acid; dimethyl sulfoxide; 1: Wittig reaction / 2: Cycloaddition / 3: Dehalogenation / 4: Condensation;

upstream raw materials:

toluene-4-sulfonic acid hydrazide

3,3-Dibutylcyclobutanone

nonanone-5

2-(1-butyl)-1-hexene