6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

Base Information

• Chemical Name: 6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS No.: 1129490-49-8
• Molecular Formula: C₁₆H₁₆Cl₂N₄O₄S
• Molecular Weight: 431.299
• Mol file: 1129490-49-8.mol

Synonyms:

Chemical Property of 6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

There total 1 articles about 6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

4-amino-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-5-mercapto-1,2,4-triazole + 3,4-dichlorbenzoic acid (51-44-5) → 6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (1129490-49-8)

Guidance literature:

In N,N-dimethyl-formamide; at 120 ℃; for 0.75h; microwave irradiation;

DOI:10.1080/15257770802088829

Reference yield: 73.0%

6-(3,4-dichlorophenyl)-3-(1,2-O-isopropylidene-D-ribo-tetritol-1-yl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (1129490-49-8) → 6-(3,4-dichlorophenyl)-3-(D-ribo-tetritol-1-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole (1129490-57-8)

Guidance literature:

With acetic acid; at 80 ℃; for 12h;

DOI:10.1080/15257770802088829

upstream raw materials:

3,4-dichlorbenzoic acid

Downstream raw materials:

6-(3,4-dichlorophenyl)-3-(D-ribo-tetritol-1-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole