2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole

Base Information

Chemical Name:2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole
CAS No.:103788-68-7
Molecular Formula:C12H12N2O3S
Molecular Weight:264.305
Hs Code.:
DSSTox Substance ID:DTXSID50547430
Wikidata:Q82425645
Mol file:103788-68-7.mol

Synonyms:2-methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole;103788-68-7;SCHEMBL6489114;DTXSID50547430;QAXAIHBOGAARQY-UHFFFAOYSA-N;2-methyl-4-[2-(4-nitrophenoxy) ethyl]-1,3-thiazole

Suppliers and Price of 2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:264.05686342
Heavy Atom Count:18
Complexity:277

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CS1)CCOC2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole

There total 1 articles about 2-Methyl-4-[2-(4-nitrophenoxy)ethyl]-1,3-thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121357-04-8
2-(2-methylthiazol-4-yl)ethanol

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 103788-68-7
2-Methyl-4-[2-(4-nitro-phenoxy)-ethyl]-thiazole

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1021/jm00092a012

Reference yield:

: 103788-68-7
2-Methyl-4-[2-(4-nitro-phenoxy)-ethyl]-thiazole

: 141399-31-7
4-[2-(2-Methyl-thiazol-4-yl)-ethoxy]-phenylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; Ambient temperature;
DOI:10.1021/jm00092a012

Reference yield:

: 103788-68-7
2-Methyl-4-[2-(4-nitro-phenoxy)-ethyl]-thiazole

: 2-Bromo-3-{4-[2-(2-methyl-thiazol-4-yl)-ethoxy]-phenyl}-propionic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10 percent Pd/C / methanol / Ambient temperature

2: 1.) aq. NaNO₂, aq. HBr, 2.) Cu₂O / 1.) MeOH, acetone, 5 deg C, 30 min, 2.) MeOH, acetone, 38 deg C

With copper(I) oxide; hydrogen bromide; hydrogen; sodium nitrite; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00092a012